宫颈鳞癌三维彩色血管定量与病理分级及微血管密度的相关性研究  

Correlation of cervical squamous cell carcinoma vascular quantitative three-dimensional color and pathological grading and micro-vessel density

作　　者：张红彬[1] 栗河舟[1] 郝志伟[1] 郭丽亚[1] 

机构地区：[1]郑州大学第三附属医院,河南郑州450000

出　　处：《中国临床医学影像杂志》2016年第8期570-572,共3页Journal of China Clinic Medical Imaging

基　　金：河南省教育厅科学技术研究重点项目(14A320025)

摘　　要：目的：探讨宫颈鳞癌血流灌注指标血管指数（Vascularizationindex，VI）与病理分级及微血管密度（Microvasculardensity，MVD）的相关性。方法：57例宫颈鳞癌患者，采用三维彩色血管能量成像技术（Three-dimensionalcolorpowerangiogra-phy，3D-CPA）在术前对癌组织内血管进行三维重建，将其与病理分级及MVD值进行分析。结果：57例宫颈鳞癌患者VI与MVD呈正相关（r=0．612，P〈0．05），术后各病理组织学分级Ⅰ～Ⅲ级与VI、MVD比较，差异有统计学意义（P〈0．05），随病理组织学分级的增高，VI、MVD亦增高。结论：VI与宫颈鳞癌病理分级及MVD旱正相关，3D-CPA能够在术前对肿瘤血供进行定量分析，为临床医生术前评估宫颈鳞癌分级提供有力证据。Objective： To explore the correlation of perfusion index vascularization index（VI）, pathological grading and mi- erovascular density （MVD） cervical squamous cell carcinoma. Methods： Fifty-seven cases of cervical squamous cell carcinoma patients, three-dimensional color power angiography（3D-CPA） was used for reconstruction of blood vessels within cancerous tis- sue in the preoperative patients, and analyzed pathological grade and MVD value. Result： There was positively correlation be- tween VI and MVD（r=0.612, P〈0.05） in the 57 cases with cervical squamous cell carcinoma. There was statistically significant difference among them by comparing pathological grade Ⅰ-Ⅲ with VI and MVD （P〈0.05）, and with value of the VI, MVD had increased, the pathology grade would be high. Conclusions： It was positively correlated VI, histological grade and MVD in patients with cervical squamous cell. 3D-CPA may provide quantitative analysis for clinical doctor, and assess the grade of cervical squamous cell before surgery clinicians.

关 键 词：宫颈肿瘤 超声检查 

分 类 号：R737.33[医药卫生—肿瘤] R445.1[医药卫生—临床医学]