不同浓度乙醇对当归保肝活性成分超声提取的影响  

Effect of Ethanol at Different Concentrations on Liver Protection Active Components in Angelica Sinensis Extracted by Ultrasonic Wave

作　　者：王元[1] 秦龙[1] 李平[1,2] 李玉民[1,2] 

机构地区：[1]兰州大学第二医院,兰州730030 [2]甘肃省消化系肿瘤重点试验室

出　　处：《中国药师》2016年第8期1479-1482,共4页China Pharmacist

基　　金：甘肃省自然科学基金项目(编号:145RJZA207);兰州大学第二医院2015年度院内博士基金项目(编号:ynbskyjj2015-2-17);兰州大学第二医院院内中医药科研项目(编号:YJzy2013-26)

摘　　要：目的:考察不同浓度乙醇对当归保肝活性成分超声提取的影响。方法:以阿魏酸含量和当归多糖含量作为考察指标,采用单因素试验分别考察20%,30%,40%,50%,60%及70%梯度浓度的乙醇对当归保肝活性成分超声提取的影响。结果:以30%乙醇为溶剂时取得了较好的效果,超声提取最佳条件为加12倍的30%乙醇,60℃超声提取4次,每次1.5 h。结论:以30%乙醇作为溶剂超声提取当归保肝活性成分最佳。Objective： To investigate the impact of ethanol at different concentrations on liver protection active components in Angelica sinensis extracted by ultrasonic wave. Methods： Ferulic acid and Angelica sinensis polysaccharide were determined as the indices,the ethanol concentration in the ultrasonic extraction was optimized by single factor experiments. Results： The optimum ethanol concentration of ultrasonic extraction was 30%. The optimized ultrasonic extraction conditions were adding 12-fold amount of 30% ethanol,and ultrasonically extracted for four times with 1. 5 h each time. Conclusion： The ultrasonic extraction of liver protection active components in Angelica sinensis with 30% ethanol is reasonable and practicable.

关 键 词：当归 保肝活性成分 阿魏酸 当归多糖 

分 类 号：R284.2[医药卫生—中药学]