微创介入技术治疗脊柱转移瘤的现状和展望  

Minimally-invasive interventional technique for the treatment of spinal metastases:current situation and prospect

作　　者：冯丽帅 马旭[1] 田庆华[1] 王建波[1] 吴春根[1] 

机构地区：[1]上海交通大学附属第六人民医院介入放射科,200233

出　　处：《介入放射学杂志》2016年第8期738-742,共5页Journal of Interventional Radiology

摘　　要：脊柱转移瘤是恶性肿瘤晚期常见并发症之一。因肿瘤生长引起椎体骨质破坏,间接导致的脊柱病理性骨折是使晚期肿瘤患者产生剧烈疼痛、生存质量下降的重要因素之一。临床上,对脊柱转移瘤进行有效的治疗,提高椎体稳定性,减少病理性骨折及肿瘤压迫导致的神经症状发生,现已成为研究热点。介入治疗技术因手术创伤小、并发症少等优点逐渐成为治疗脊柱转移肿瘤的重要手段。本文对目前临床上针对脊柱转移瘤常用的介入治疗方法进行综述,并进一步展望多种微创治疗手段联合使用对缓解肿瘤脊髓压迫,减少骨性疼痛,延长患者生存时间及提高患者生存质量等方面的临床应用价值。Spinal metastasis is one of the most common complications of malignant tumors. Bone destruction caused by tumor growth is an important factor that causes severe pain and decreases the quality of life in patients with advanced cancer. Recently, the metastasis-related topics, such as the effective treatment for spinal metastatic tumors, the improvement of vertebral stability, the prevention and reduction of pathological fracture, the treatment of nerve symptoms caused by tumor compression, etc. have become the hot spots in clinical research field. Because of the advantages of less surgical trauma, less complications and so forth, the interventional therapy has gradually become an important means for the treatment of spinal metastatic tumors. This paper aims to make a comprehensive review about the various interventional treatment methods commonly used nowadays in clinical practice, and to discuss the clinical application of the combination use of various minimally-invasive treatments in relieving the spinal cord compression due to tumor, in reducing bone pain, in prolonging the survival time of patients, in improving the quality of life of patients, and the like.

关 键 词：转移瘤 脊柱 经皮椎体成形术 经导管动脉化疗栓塞术 碘放射性核素 介入治疗 联合治疗 

分 类 号：R738.1[医药卫生—肿瘤] R730.55[医药卫生—临床医学]