帕金森病认知功能障碍的量表评估及相关危险因素分析  

The scale assessment of cognitive impairment in Parkinson's disease patients and related risk factors analysis

作　　者：鲁建华[1] 

机构地区：[1]湖北省咸宁市中心医院湖北科技学院附属第一医院神经内科,437100

出　　处：《中国老年保健医学》2016年第4期16-18,共3页Chinese Journal of Geriatric Care

摘　　要：目的探讨蒙特利尔认知评估量表(MoCA)和简易智能状态检查量表(MMSE)在筛查帕金森病(PD)患者认知功能障碍中的应用,同时分析PD认知功能障碍的相关危险因素。方法分析我院120例PD患者,根据认知功能将其分为正常组(PD-NCI,60例)、轻度认知功能障碍组(PD-MCI,32例)和PD痴呆组(PDD,28例),采用Mo CA和MMSE对患者进行评估,同时分析性别、年龄、受教育年限,病程相关因素与PD认知功能障碍的关系。结果三组MoCA、MMSE得分差异有统计学意义(P<0.05)。与正常组比较,受教育程度低的老年男性PD患者似乎更易出现MCI及PDD。结论 MoCA结合MMSE可有效筛查PD患者认知功能损害。性别、年龄、受教育程度及病程可能是PD认知功能障碍的相关危险因素。Objectives To study the application of Montreal cognitive assessment（ MoCA） and mini-mental state examination（ MMSE） in screening cognitive impairment in Parkinson＇s disease（ PD） patients,and analyze related risk factors of PD cognitive impairment. Methods One hundred and twenty PD patients were divided into normal group（ PD-NCI）,mild cognitive impairment group（ PD-MCI） and PD dementia group（ PDD） according to their cognitive function. They were assessed and according to their MoCA and MMSE score,and to analyze the relationship between related risk factors of gender,age,years of education,the course of the disease and cognitive impairment. Results The MoCA and MMSE scores were significantly different in 3 groups（ P〈0.05）.Compared with normal group,MCI and PDD group have less education and more elderly male patients（ P〈0.05）. Conclusions Mo CA combined MMSE is effective in screening the cognitive impairment in Parkinson＇s disease patients. Gender,age,level of education and course may be related risk factors of PD cognitive impairment.

关 键 词：帕金森 认知功能 痴呆 

分 类 号：R742.5[医药卫生—神经病学与精神病学]