运用磁共振T2图动态观察正常人体足三里穴微创埋线后线体对局部的刺激效应  

Dynamic Changes of Fast Spin-echo T2 Weighted Images Displayed Topical Reactions to Micro-invasive Catgut-embedment of Zusanli(ST 36)in Healthy Volunteer Subjects

作　　者：梁欣[1] 聂红昉[2] 候珣瑞 吕明庄[1] 

机构地区：[1]贵州医科大学附属医院针灸科,贵阳550004 [2]贵州医科大学附属医院影像科,贵阳550004

出　　处：《针刺研究》2016年第4期356-360,共5页Acupuncture Research

基　　金：贵州省卫生厅中医药管理局项目(No.QZYY 2013-86)

摘　　要：目的:在体、动态观察分析微创埋线后线体对正常人体经穴局部刺激效应的时效特点,为微创埋线疗法间隔周期提供参考依据。方法:应用医学影像学磁共振(MR)扫描技术,采集8例正常人体左侧足三里穴埋线前、后多个时间点局部轴位T2 加权(T2 WI)压脂像及T2 图(T2 -mapping)8回波序列MR图像,所得8回波系列图像利用FuncTool软件生成T2 -mapping图像后测量埋线局部T2 值,分析足三里穴微创埋线后局部T2 WI压脂像信号强度及T2 值随时间变化的特点。结果:与埋线前相比,埋线后8h局部T2 WI压脂像信号强度及T2 值开始升高,埋线后第3日局部T2 WI压脂像信号强度及T2 值明显升高,埋线后第7、14日局部T2 WI压脂像信号强度及T2 值较埋线后第3日下降,但仍高于埋线前,至埋线后第21、28、35天,埋线局部T2 WI压脂像信号强度及T2 值下降至接近埋线前。T2 值经统计学处理显示:埋线后8h,第3、7、14天皆明显高于埋线前(P<0.01);埋线后第21、28、35天与埋线前比较差异均无统计学意义(P>0.05)。结论:施行微创埋线后,线体对足三里穴的刺激效应周期为21d左右。相同条件下施行微创埋线时,选用与足三里穴结构相近的穴位,其埋线间隔周期以21d左右为宜。Objective To observe the duration of local reactions after subcutaneous micro-invasive catgut-embedding stimulation in Zusanli（ST 36）region in normal human body by using magnetic resonance（MR）T2 -mapping,so as to find a reasonable interval between every two catgut-embedding performance.Methods A total of 8normal volunteers（3women,and 5men）were enrolled in the present study.Before and 8h,and 3,7,14,21,28 and 35days after the subcutaneous micro-invasive embedment of catgut（Gauge 2.0,2cm long）in the left Zusanli（ST 36）area,the local T2 -weighted images（T2 WI）and fatsuppression T2 -weighted images（FS T2 WI）were detected and recorded by using MR scan（GE Optima MR 360 1.5T）and analyzed using FuncTool software.Results Compared with pre-catgut-embedment,the local signal strength of T2 FS WI and T2 relaxation time began to rise on the 8th hour after catgut-embedment,peaked on the 3rd day,began to descend on the 7th day,but being still higher than pre-embedment,and turned to the normal level on the 21 st day to the 35 th day.Results of statistical analysis displayed that compared with pre-catgut-embedment,T2 relaxation time levels were significantly higher on the 8th h,day 3,7and 14 after the embedment（P〈0.01）,and were comparable to that of pre-embedment on day 21,28 and 35（P〈0.05）.Conclusion Catgut-embedment of Zusanli（ST 36）induces an apparent change of MRI signals from the 8th h to the 14 th day in normal volunteer subjects,suggesting that an interval of 21 days may be reasonable for the micro-invasion catgut-embedment in clinical practice.

关 键 词：微创埋线 磁共振成像 T2图 足三里穴 

分 类 号：R224[医药卫生—中医基础理论]