对比腹腔镜与开腹手术途径治疗早期宫颈癌的Meta分析  

Laparoscopy Versus Laparotomy for the Management of Early-stage Cervical Cancer:A Meta-analysis

作　　者：赵际童[1] 周圣涛[1] 边策[1] 赵霞[1] 

机构地区：[1]四川大学华西第二医院出生缺陷与相关妇儿疾病教育部重点实验室,四川成都610041

出　　处：《实用妇产科杂志》2016年第8期618-622,共5页Journal of Practical Obstetrics and Gynecology

基　　金：国家基础研究项目(973项目)(编号:2010CB529905);四川省医学科研青年创新课题(编号:Q14038)

摘　　要：目的:对比腹腔镜与开腹两种手术途径行根治性子宫切除术(RH)治疗早期宫颈癌的近期疗效差异。方法:计算机检索Pub Med、Cochrane图书馆,检索时限为1990年1月至2015年3月,纳入比较两种手术途径行RH治疗早期宫颈癌的前瞻性比较性研究,采用Rev Man 5.1软件进行Meta分析。结果:最终纳入6篇前瞻性比较性研究,共计449例宫颈癌患者。Meta分析结果示:两种手术途径在术后复发率、手术出血量、手术时间、手术并发症、盆腔淋巴结切除数量、住院时间等方面差异无统计学意义(P>0.05)。纳入文献无明显异质性和发表偏倚。结论:与开腹途径相比,腹腔镜途径RH不增加术后复发和手术并发症风险。Objective.To compare short-term outcomes of laparoscopic radical hysterectomy（LRH） and ab- dominal radical hysterectomy（ARH） for patients with early-stage cervical cancer. Methods：PubMed and the Co- chrane Library databases were searched for published prospective studies from January 1990 to March 2015. Outcomes were pooled and meta-analyses were performed with RevMan software （version 5. 1 ）. Results： Six prospective studies with 449 patients were identified. No significant difference was observed in recurrence, estimated blood loss,operation time, perioperative complications, amount of pelvic lymph nodes, or length of stay（ P 〉 0.05）. Besides,significant heterogeneity or publication bias was not found. Conclusions：Compared with ARH, LRH might not increase the risk of recurrence or perioperative complications.

关 键 词：腹腔镜 开腹手术 早期宫颈癌 根治性子宫切除术 META分析 

分 类 号：R737.33[医药卫生—肿瘤]