参芪扶正注射液联合EP方案治疗非小细胞肺癌临床研究  

Clinical study on the treatment of non small cell lung cancer with the combination of Shenqi Fuzheng injection and EP chemotherapy

作　　者：石秀全[1] 徐丽君[2] 

机构地区：[1]安徽省颍上县人民医院普外科,236200 [2]安徽省颍上县人民医院肿瘤内科,236200

出　　处：《中国基层医药》2016年第17期2580-2583,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：安徽省卫生和计划生育委员会中医药科研课题（2014zy94）

摘　　要：目的：观察参芪扶正注射液联合 EP 方案治疗 NSCLC 在生存质量、毒副作用改善方面的作用。方法将60例 NSCLC 患者用随机数字表法分为观察组和对照组，每组各30例，两组均采用 EP 方案治疗。观察组加用参芪扶正注射液，共治疗2个疗程，观察两组生存质量和不良反应。结果观察组与对照组治疗后生存质量改善有效率差异有统计学意义（93．3％比70．0％，χ^2＝2．83，P ＜0．05），观察组生存质量明显高于对照组。两组白细胞减少、贫血和肝肾功能损害方面差异有统计学意义（P ＝0．011、0．025、0．016）。结论参芪扶正注射液联合 EP 方案治疗 NSCLC，在生存质量、毒副作用改善方面的具有较好的效果，可作为中西医结合治疗 NSCLC 患者的一种手段，在临床推广应用。Objective To observe the therapeutic effect of Shenqi Fuzheng injection combined with EP chemotherapy in the treatment of non small cell lung cancer （NSCLC）,and to improve the quality of life and side effects.Methods 60 cases of NSCLC were randomly divided into observation group and control group,30 cases in each group.The two groups were treated with EP,the observation group was treated with Shenqi Fuzheng injection for two courses.The life quality and adverse effects were observed.Results The quality of life of the two groups after treatment was compared,the difference was statistically significant （93.3% vs 70.0%,χ^2 =2.83,P 〈0.05）,the quality of life in the observation group was significantly higher than that in the control group.The white blood cell reduction,anemia and liver and kidney function damage between the two groups had statistically significant differences （P =0.011,0.025,0.016）,the adverse reaction of the observation group was less than the control group.Conclusion Shenqi Fuzheng injection combined with EP regimen in the treatment of NSCLC can protect bone marrow hematopoietic function and improve the quality of life of patients with NSCLC chemotherapy.It can be used as one mean of Chinese and western treatment for patients with NSCLC in clinical application.

关 键 词：癌 非小细胞肺 抗肿瘤联合化疗方案 益气扶正 

分 类 号：R734.2[医药卫生—肿瘤]