探讨手术对海马硬化型颞叶癫痫的疗效  

To Investigate the Effect of Surgical Treatment on Hippocampal Sclerosis Type Temporal Lobe Epilepsy

作　　者：段宝奇[1] 傅传经[1] 高觉民[1] 

机构地区：[1]江苏省中医院神经外科,江苏南京210029

出　　处：《中国继续医学教育》2016年第23期95-97,共3页China Continuing Medical Education

基　　金：江苏省中医药局科技项目(编号:LZ13036);江苏省中医院科技项目(编号:Y13001)

摘　　要：目的探讨手术对海马硬化型颞叶癫痫患者的癫痫发作和认知功能的影响。方法对2006年1月-2013年12月我科进行手术治疗的26例海马硬化型颞叶癫痫患者的癫痫发作Enge1分级和韦氏智力量表进行回顾性分析。结果 26例患者术后Enge1 I级20例,Ⅱ级4例,Ⅲ级2例;总智商和操作智商分别为（98.5±7.6）分和（49.7±5.2）分,优于术前（82.7±6.4）分和（35.4±4.2）分（P〈0.05）;Enge1 I级患者的总智商、操作智商、言语智商分别为（102.6±8.9）分、（51.7±5.8）分、（50.6±6.1）分,优于其他患者的（87.9±7.1）分、（40.4±4.2）分、和（43.5±4.9）分（P〈0.05）。结论手术治疗海马硬化型颞叶癫痫有助于控制癫痫发作和改善认知功能。Objective To investigate the seizure outcome and cognitive function in patients with temporal lobe epilepsy with surgical treatment. Methods 26 cases with temporal lobe epilepsy, who were treated temporal anterior lobe ＋hippocampus amygdala resection during the period from June 2006 to December 2013. Their Engel class and cognitive function were analyzed in the follow-up time. Results The seizure outcomes according to Engel outcome scale were Ⅰ grade in 20 cases, Ⅱ in 4, Ⅲ in 2. The FIQ and PIQ according to Wechsler Intelligence Scale was respectively（98.5±7.6）,（49.7±5.2） better than（82.7±6.4）,（35.4±4.2）（P〈0.05） before operation, and FIQ, PIQ, VIQ was respectively（102.6±8.9）,（51.7±5.8）,（50.6±6.1）in Enge1 I grade better than（87.9±7.1）,（40.4±4.2）,（43.5±4.9）（P〈0.05） in other patients. Conclusion Patients with temporal lobe epilepsy can benefit from surgical treatment.

关 键 词：手术 癫痫 认知功能 疗效 

分 类 号：R742[医药卫生—神经病学与精神病学]