小肠间质瘤45例临床诊治分析  

Clinical analysis of 45 cases of small intestinal stromal tumor

作　　者：韩鸿彬[1] 王公平[1] 陈晔[1] 汪增方 金灿辉[1] 

机构地区：[1]河南科技大学第一附属医院胃肠肿瘤外科,河南洛阳471003

出　　处：《中国现代医学杂志》2016年第17期121-124,共4页China Journal of Modern Medicine

摘　　要：目的探讨小肠间质瘤(SIST)的临床表现和诊治方法。方法回顾性分析2005年9月-2010年9月该院收治45例经病理组织学确诊的SIST患者临床、病理和随访资料。结果 SIST的临床表现无特异性,消化道出血、贫血、腹部包块或小肠梗阻是其主要表现。好发部位最常见依次为空肠、十二指肠和回肠。术前诊断率为80%(36/45),根治性切除率为84.44%(38/45),无围手术期死亡,所有病例均经手术和病理学证实。结论 SIST无特异性临床症状,CT检查有一定的诊断价值,CD117和CD34有助于诊断,积极外科手术切除和甲磺酸伊马替尼辅助治疗可获得良好效果。Objective To investigate the clinical manifestation, diagnosis and treatment of small intestinal stromal tumor （SIST）. Methods Forty-five patients with pathologically confirmed SIST from September 2005 to September 2010 were enrolled into this study. Their clinical, pathological and follw-up data were retrospec- tively analyzed. Results The clinical features of SIST were non-specific, the main manifestations were gastro- intestinal bleeding, anemia, abdominal mass and small bowel obstruction. The most common sites were jejunum, duodenum and ileum. All of them underwent operations with a preoperative diagnostic rate of 80% （36/45）. The radical resection rate was 84.44% （38/45）. And no death occurred during perioperative period, all the cases were confirmed by surgery and pathology. Conclusions SIST does not have specific clinical symptoms. CT examination has importent diagnostic value, and CDl17 and CD34 contribute to the diagnosis. Positive surgi- cal resection and Imatinib mesylate adjuvant therapy can give good results.

关 键 词：小肠间质瘤 诊断 治疗 

分 类 号：R735.32[医药卫生—肿瘤]