肺癌前血栓状态的研究进展  

Research advances of prethrombotic state in lung cancer

作　　者：丁洁[1] 崔林[1] 

机构地区：[1]泰州市第二人民医院肿瘤科,江苏泰州225500

出　　处：《现代肿瘤医学》2016年第19期3154-3157,共4页Journal of Modern Oncology

基　　金：江苏省泰州市科技发展计划项目(编号:2013068);江苏大学医学临床科技发展基金项目(编号:JLY20140144);江苏省泰州市高层次人才科研项目基金(编号:2015013)

摘　　要：前血栓状态是由多种病理因素引起的凝血与抗凝血系统、纤溶系统平衡失调,血液黏滞性增高,有利于血栓形成的一种病理生理状态。前血栓状态形成机制复杂,临床上与肺癌关系密切,是血栓事件相关的原因,同时与肿瘤复发、转移相关。抗凝治疗可能成为抗肿瘤治疗的途径之一,可以减少血栓事件的发生率,影响肿瘤的复发、转移,提高病人的生活质量。Prethrombotic state refers to a pathophysiological process of coagulation,anti-coagulation and fibrinolysis system disorders caused by multiple pathologic factors,which leads to thrombus formation and the increase of blood viscosity.The formation mechanism of prethrombotic state is complicated.It has close relationship with the invasion, recurrence and metastasis of lung cancer and results in the prethrombotic events.So,anticoagulation therapy which can decrease the risk of prethrombotic events and reduce the recurrence and metastasis of tumor may become a new ap-proach for antitumor and improve living quality of lung cancer patients.

关 键 词：前血栓状态 肺恶性肿瘤 静脉血栓栓塞 抗凝治疗 

分 类 号：R734.2[医药卫生—肿瘤]