支气管肺泡灌洗液及纤支镜刷片在肺癌诊断的应用  

Assessment of bronchial brush cytology and bronchoaleolar lavage fluid cytology in diagnosis of lung cancer

作　　者：李莘[1] 王咏梅[1] 乔春丽[1] 邢杞[1] 

机构地区：[1]天津市海河医院病理科(天津市呼吸疾病研究所),天津300350

出　　处：《中国城乡企业卫生》2016年第8期134-136,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：目的探讨支气管肺泡灌洗液(BAL)和纤维支气管镜刷片在肺癌诊断的作用。方法对天津市海河医院27例疑为肺癌并进行了纤维支气管镜检查患者的细胞病理学特征进行分析和评价。结果 27例患者中,组织学确诊肺癌11例(40.74%),其中包括鳞状低胞癌8例(72.73%),腺癌2例(18.18%),小细胞肺癌1例(9.09%);纤维支气管镜刷片的敏感性为45.45%,特异性为87.50%;灌洗液敏感性为36.36%,特异性为93.75%。两者准确率相同,70.37%。结论在肺癌的诊断中支气管肺泡灌洗液BAL及纤维支气管镜刷片细胞病理学检查,但缺少良好的敏感性具有相对较高的特异性。Objective To assess the accuracy of bronchial brush cytology and bronchoalveolar lavage fluid cytology in diagnosis of lung cancer at our hospital. Methods To collect 27 patients who were suspected of having lung cancer and had undergone fiberoptic bronchoscopy of Tianjin Haihe hospital and assess the cytology diagnostic value. Results Among the 27 cases. Lung biopsy identified malignancy in 11 cases （40.74%）, including 8 cases（72.73%）with squamous cell carcinoma, 2cases（18.18%） its with adenocarcinoma, 1 case （9.09%）with small cell carcinoma. The sensitivity of brush cytology was 45.45% and. specificity was 87.50%. The sensitivity of brochoalveolar lavage was 36.36% and its specificity was 93.75%. The accuracy of both brush and brochoalveolar lavage fluid was the same, 70.37%. Conclusion Bronchial brush cytology and bronchoalveolar lavage fluid cytology have high specificity but not sensitivity in diagnosis of lung cancer.

关 键 词：支气管肺泡灌洗液 纤支镜刷片 肺癌 敏感性 特异性 

分 类 号：R365[医药卫生—病理学]