玻璃体腔内注射康柏西普治疗黄斑水肿临床观察  

Intravitreal injection of Conbercept for macular edema

作　　者：张静慧[1] 冯彩霞[1] 谷华丽[1] 

机构地区：[1]漯河医学高等专科学校第三附属医院眼科,河南漯河462000

出　　处：《中华实用诊断与治疗杂志》2016年第9期931-932,共2页Journal of Chinese Practical Diagnosis and Therapy

摘　　要：目的探讨康柏西普治疗因视网膜静脉阻塞所致黄斑水肿的临床疗效和安全性。方法 44例黄斑水肿患者依据治疗方法分为观察组22例和对照组22例,对照组给予常规激光光凝治疗,观察组在激光光凝治疗7d后行康柏西普玻璃体腔内注射。治疗3个月后评定2组疗效,观察并发症发生情况。结果观察组治疗总有效率(95.45%)高于对照组(63.64%),并发症发生率(13.64%)低于对照组(40.91%),差异均有统计学意义(P<0.05)。结论对因视网膜静脉阻塞所致的黄斑水肿,在常规激光光凝治疗基础上联合康柏西普玻璃体腔内注射临床疗效满意,并发症发生率低。Objective To investigate the therapeutic effect and safety of intravitreal injection of Conbercept in thetreatment of macular edema induced by retinal vein obstruction. Methods Forty-four patients with macular edema weredivided into observation group and control group, with 22 patients in each group. Control group received laserphotocoagulation therapy and observation group received intravitreal injection of Conbercept after 7-day treatment of laser photocoagulation therapy. The therapeutic effect was evaluated in two groups after 3-month treatment and the adversereactions were observed. Results The total effective rate was significantly higher and the incidence of adverse reactionswas significantly lower in observation group （95.45%, 13.64%） than those in control group （63.64%, 40.91%） （P〈0. 05）. Conclusion Intravitreal injection of Conbercept plus laser photocoagulation is effective for macular edema inducedby retinal vein obstruction and the incidence of adverse reaction is low.

关 键 词：黄斑水肿 激光光凝 康柏西普 

分 类 号：R774.5[医药卫生—眼科]