大脑中动脉狭窄的动态演变与其周围微小血管的关系  

The Association between Dynamic Changes of MCA Stenosis and Its Surrounding Small Vessels in Brain

作　　者：郑博文[1] 许玉园 李明利[2] 高山[1] 冯逢[2] 徐蔚海[1] 

机构地区：[1]北京协和医院神经内科,北京100730 [2]北京协和医院放射科,北京100730

出　　处：《中国卒中杂志》2016年第8期626-630,共5页Chinese Journal of Stroke

基　　金：教育部新世纪优秀青年基金(NCET-12-0069);北京协和医学院青年基金;中央高校青年基金;国家自然科学基金(81471207);首都卫生发展科研专项基金(2014-4-4015)

摘　　要：目的探讨用高分辨磁共振成像(high-resolution magnetic resonance imaging,HRMRI)随访大脑中动脉(middle cerebral artery,MCA)狭窄或闭塞病例时发现的MCA狭窄或闭塞与其周围微小血管的关系。方法收集2007年7月-2015年3月于北京协和医院因MCA狭窄或闭塞多次行HRMRI检查的病例(共20例),分析其MCA狭窄或闭塞的变化与其周围微小血管的关系。结果 20例患者中7例的MCA由狭窄转变为闭塞(35.00%),其中有6例出现狭窄或闭塞周围微小血管(85.71%);13例MCA的狭窄无明显变化,其中有3例的狭窄或闭塞周围微小血管状况出现变化(23.08%);两组比较差异具有显著性(P=0.02)。结论大脑中动脉狭窄或闭塞的周围微小血管可能与狭窄度的加重相关。Objective To analyze the relationship between the stenotic or occluded middle cerebral artery（MCA） and a newly discovered imaging phenomenon, which called small vessels around stenotic or occluded site（SVSOS）, in patients with multiple high-resolution magnetic resonance imaging（HRMRI） examinations.Methods Retrospectively reviewed 20 patients with multiple HRMRI examinations for MCA stenosis or occlusion in Peking Union Medical College from July 2007 to March 2015, and analyzed the relationship between stenotic or occluded MCA and SVSOS.Results Seven patients＇ MCA changed from stenosis to occlusion with multiple HRMRI examinations（35.00%）, while 13 patients＇ MCA remained stenotic. Six cases with SVSOS were witnessed in patients with MCA change（85.71%）, while 3 patients without MCA change had SVSOS（23.08%）. There was significant difference in two groups（P =0.02）.Conclusion Small vessels around stenotic or occluded site（SVSOS） might be associated with the aggravation of stenosis degree.

关 键 词：高分辨磁共振成像 大脑中动脉 狭窄或闭塞周围微小血管 

分 类 号：R743.3[医药卫生—神经病学与精神病学]