恶性孤立性肺结节螺旋CT与PET/CT分析  

Spiral CT and PET/CT manifestations of malignant solitary pulmonary nodules

作　　者：李培秀[1] 徐晓磊[1] 都日娜[1] 李继光[1] 孟令权[1] 张强[1] 

机构地区：[1]中国石油天然气集团公司中心医院CT科,河北廊坊065000

出　　处：《医疗卫生装备》2016年第8期84-86,共3页Chinese Medical Equipment Journal

基　　金：河北省科技厅支撑项目(112761166)

摘　　要：目的 :通过分析恶性孤立性肺结节的多层螺旋CT及PET/CT影像,获得对肺内结节定性诊断有价值的影像学信息。方法:回顾性分析52例经病理证实腺癌(28例)、鳞癌(12例)、小细胞肺癌(8例)及不典型腺瘤样增生(4例)的影像资料。分析病理类型、结节密度、形态及代谢活度,并采用方差及卡方检验进行统计学分析。结果:实性结节与磨玻璃密度结节最大标准摄取值(maximum standardized uptake value,SUV_(max))差异有统计学意义(P<0.05),其中35例实性密度结节的平扫、动脉期、延迟期CT均值差异有统计学意义(F=132.365,P=0.000)。分叶征与血管集束征差异有统计学意义(P<0.05)。结论:磨玻璃结节^(18)F-FDG的低代谢不能作为否定恶性证据,实性结节强化差异显著,分叶征与血管集束征与结节恶性程度密切相关。Objective To obtain diagnostic manifestations by analyzing multi-slice spiral CT and PET/CT images of malignant solitary pulmonary nodules. Methods A retrospective analysis of 52 cases confirmed by pathology was carried out, including 28 cases of adenocarcinoma, 12 cases of squamous cell carcinoma, 8 cases of small cell lung cancer, and 4 cases of atypical adenomatous hyperplasia. Analyses were implemented on pathological type, nodular density, morphology and metabolic activity, and variance and chi square tests were used for statistical analysis. Results There were significant differences（P〈0.05）between solid nodule and glass nodule in maximum standardized uptake value（SUV_（max））. The non-contrast, arterial phase and delay phase in 35 cases of solid density nodules also had statistically significances（F =132.365,P =0.000）. Lobulation had statistically significant differences with vascular convergence sign as well. Conclusion Hypometablism of glass nodule^（18）F-FDG can not be used as the evidence to negate malignant tumor. There are significant differences between the enhancement of solid nodules, and lobulation sign and vascular convergence sign are closely correlated with the grade malignancy of the nodule.

关 键 词：孤立性肺结节 诊断 低代谢 恶性 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]