Hedgehog信号通路与动物骨骼肌发育调控  

Hedgehog Signaling Pathway in the Regulation of Animal Skeletal Muscle Development

作　　者：夏博[1] 葛静[1] 史新娥[1] 

机构地区：[1]西北农林科技大学动物科技学院动物脂肪沉积与肌肉发育实验室,陕西杨凌712100

出　　处：《中国生物化学与分子生物学报》2016年第9期994-997,共4页Chinese Journal of Biochemistry and Molecular Biology

基　　金：国家重点基础研究发展计划(973计划;No.2015CB943102)资助~~

摘　　要：Hedgehog信号通路在动物胚胎期及出生后骨骼肌的生长发育过程中发挥着重要作用。本文综述了Hedgehog信号通路对骨骼肌细胞增殖分化及肌纤维特性的调控作用及其在骨骼肌发育过程中与其它信号通路交互作用最新研究进展,为畜禽肉品质改良和肌肉相关疾病治疗提供理论基础。Hedgehog signaling pathway plays an important role in embryonic and postnatal growth and development of skeletal muscle. This article reviewed the latest research progress on the role of the Hedgehog signaling pathway in myocyte proliferation and differentiation,and its interaction with other signaling pathways in skeletal muscle development. It will provide the fundamental basis for the improvement of livestock and poultry meat quality and the therapy of skeletal muscle disease.

关 键 词：HEDGEHOG信号通路 骨骼肌 增殖分化 肌纤维特性 

分 类 号：S813[农业科学—畜牧学]