血液学课程MICM资源库的建设与应用  

Construction and application of MICM resource library in teaching of hematologic diseases

作　　者：王真真[1] 左学兰[1] 吴三云[1] 刘莉[1] 沈辉[1] 陈飞[1] 

机构地区：[1]武汉大学第二临床学院内科学教研室,武汉大学中南医院血液科,武汉430071

出　　处：《中国医学教育技术》2016年第5期542-544,共3页China Medical Education Technology

基　　金：武汉大学医学部教学研究项目(2015028)

摘　　要：目的建立和应用血液学课程MICM资源库,提高教学效果。方法收集临床常见的各种血液病患者的骨髓和外周血,常规方法制片,Wright染色后显微镜下观察形态学(morphology,M),流式细胞仪方法检测细胞免疫表型(immunology,I),G带方法制作细胞遗传学核型(cytogenetics,C),分子生物学方法(molecular biology,M)检测融合基因及基因突变,再将这些标本和结果制作成血液学MICM电子资源数据库并应用于教学和实习。结果建立了专门用于教学的血液学资源库,通过在不同学习阶段的学生中应用,增加了学生学习的积极性和主动性,提高了血液学教学效果及质量。结论建立和应用血液学MICM资源库有利于提高血液学教学质量,并对内科学教学资源平台建设具有借鉴意义。Objective To construct MICM （ morphology, immunology, cytogenetics, and molecular biology） resource library and improve teaching effectiveness of hematologic diseases. Methods Peripheral blood and bone marrow were obtained from patients with typical hematologic diseases. Cell morphology was determined with Wright stain, and flow cytometry was used to detect immunophenotype of the cells. Karyotype of bone marrow was analyzed by G-banding, and fusion gene transcript was detected by molecular biology technique. All slides, observed and scanned under the electron microscope together with electronic resource, were collected and categorized for MICM resource library. The MICM resource library was then used for teaching of hematologic diseases and clinical practice. Results MICM resource library was successfully constructed and used in the teaching of hematologic diseases, which increased students ^ learning enthusiasm and initiative, and improved the efficiency and quality of teaching. Conclusion Construction and application of MICM resource library can help improve teaching effectiv-eness of hematologic diseases, and may serve as reference for the construction of internal medicine teaching resource platform.

关 键 词：血液学 MICM资源库 教学改革 

分 类 号：G434[文化科学—教育学]