振源止痫汤治疗小儿癫痫的临床效果观察  

Zhenyuanzhixian decoction in treatment of epilepsy in children

作　　者：肖春光 尹爱良 王永强 

机构地区：[1]威海市中心医院儿科,264400

出　　处：《国际医药卫生导报》2016年第18期2838-2840,共3页International Medicine and Health Guidance News

摘　　要：目的探讨振源止痫汤治疗小儿癫痫的临床疗效。方法将住院的需药物治疗的65例癫痫患儿数字化随机分成治疗组32例和对照组33例。治疗组振源止痫汤治疗，对照组一线抗癫痫药卡马西平、丙戊酸钠治疗。利用统计学方法分析比较两组癫痫控制的总有效率、智商（IQ）的差异。结果治疗组临床疗效优于对照组。治疗组癫痫完全控制26例，显效3例，有效1例，无效2例；对照组癫痫完全控制19例，显效2例，有效3例，无效9例。两组总有效率比较，差异有统计学意义（X^2=5．10，P〈0．05）。治疗组智商（IQ）（93．70±5．67），对照组（78．50±7．82），差异有统计学意义（t=8．99，P〈0．05）。结论振源止痫汤治疗小儿癫痫能有效控制癫痫发作，减轻认知功能损害，提高智商，值得临床推广应用。Objective To observe the clinical effect of Zhenyuanzhixian decoction in the treatment of epilepsy in children. Methods 65 children with epilepsy were randomly divided into a control group （n=33） and a treatment group （n=32） randomly. The control group were treated with carbamazepine and sodium valproate and the treatment group Zhenyuanzhixian decoction. The clinical total effective rate and IQ were compared between these two groups. Results 26 cases were complete controlled, 3 cases controlled, 1 cases basicly controlled, and 2 cases not controlled in the treatment group; 19 cases were complete controlled, 2 cases controlled, 3 cases basicly controlled, and 9 cases not controlled in the control group; the total effective rate was higher in the treatment group than in the control group, with a statistical difference （X 2=5.10, P〈 0.05）. The IQ was （93.70±5.67） in the treatment group and （78.50±7.82） in the control group, with a statistical difference （t=8.99, P〈 0.05）. Conclusions Zhenyuanzhixian decoction in the treatment of epilepsy in children can reduce the epilepsy paroxysm frequency and improve IQ without increasing adverse reactions, so it is worth being clinically generalized.

关 键 词：振源止痫汤 小儿癫痫 智商(IQ) 

分 类 号：R742.1[医药卫生—神经病学与精神病学]