头颈部侵袭性纤维瘤病的治疗  

Treatment of Aggressive Fibromatosis in Head and Neck Region

作　　者：曹俊[1] 孙国文[1] 朱锋[1] 

机构地区：[1]南京大学医学院附属口腔医院颌面外科,江苏南京210008

出　　处：《口腔医学研究》2016年第9期941-943,共3页Journal of Oral Science Research

基　　金：基金项目江苏省临床医学科技专项项目(编号:BL2012017,BL2013005);江苏省卫生厅课题项目(编号:H201441)

摘　　要：目的：评估头颈部侵袭性纤维瘤病的诊断、治疗和预后。方法：对2001~2014年我科手术治疗的头颈部侵袭性纤维瘤病患者作回顾性研究。结果：根据2005年世界卫生组织的诊断标准,本文共报道了9例头颈部侵袭性纤维瘤病患者,随访至今6例未见复发,3例复发。结论：头颈部结构复杂,手术操作空间有限,推荐切除安全边界为0.5~1cm。对于能够手术完整切除的病例,术后随访结果较为满意,但肿瘤复发的可能性仍存在;对于肿瘤邻近重要解剖结构无法完整切除者,推荐肿瘤部分切除结合术后放疗。远期治疗效果仍需要进一步随访、观察。Objective：To evaluate the diagnosis,treatment and prognosis of aggressive fibromatosis in head and neck region.Methods：Patients with aggressive fibromatosis in head and neck region from 2001 to 2014were treated by operation and retrospectively studied in our department.Results：According to the diagnostic criteria of WHO in2005,9cases of patients with aggressive fibromatosis occurred in head and neck region.So far,3cases relapsed.Conclusion：The head and neck structures were complex and operation space was limited.The recommended safe margin was 0.5~1cm.For patients with complete resection,the prognosis was satisfactory,but tumor recurrence might still exist.If the lesions were adjacent to the important anatomic structure,partial resection combined with postoperative radiotherapy was suggested,and the long-term curative effect needed to be further investigated.

关 键 词：侵袭性纤维瘤病 局部扩大切除 放疗 

分 类 号：R739.91[医药卫生—肿瘤]