剪切波组织定量技术在肝肿瘤诊断中的应用价值及影响因素分析  

Evaluation of the feasibility of shear wave point quantification technology in the diagnosis of liver tumors as well as its impact factors

作　　者：韩红[1] 徐亚丹[1] 胡浩[1] 王文平[1] 丁红[1] 陆清[1] 

机构地区：[1]复旦大学附属中山医院超声科上海市影像医学研究所,上海200032

出　　处：《中华超声影像学杂志》2016年第9期767-770,共4页Chinese Journal of Ultrasonography

基　　金：上海市卫计委基金（20134085）;国家自然科学基金（81371577,81571675）

摘　　要：目的探讨剪切波组织定量技术在肝肿瘤诊断中的应用价值及主要影响因素。方法应用超声对129例肝肿瘤患者的129个肝内肿瘤进行检查并比较肝肿块弹性值及弹性比值对肝肿瘤良恶性的诊断价值。结果肝恶性肿瘤弹性值及弹性比值均高于良性肿瘤（P〈0.05）。以弹性值〉1.40 m/s诊断肝恶性肿瘤，ROC曲线下面积为0.78；以弹性比值〉1.05诊断肝恶性肿瘤，ROC曲线下面积为0.63。不同大小、肝左右叶不同位置、不同肝纤维化背景下肝恶性肿瘤弹性值及弹性比值差异无明显统计学意义（P〉0.05）。结论剪切波组织定量技术可以帮助鉴别肝恶性肿瘤。肿瘤大小、位置、是否有肝硬化背景对肝恶性肿瘤超声弹性值的测定无明显影响。Objective To evaluate the feasibility of shear wave point quantification technology in the diagnosis of liver tumors as well as its impact factors. Methods One hundred and twenty-nine intra-hepatic liver tumors were included in the study. Elastic value and elastic ratio were used to compare on the accuracy of diagnosis of benigh and malignant liver tumors with Philips-EPIQ7 ultrasound system. Results Both elastic value and elastic ratio of malignant liver tumors were higher than those of benigh tumors （ P 0.05） ;and their cutoff values were 1.40 m/s and 1.05 respectively. The area under the ROC curve for elastic value and elastic ratio were 0.78 and 0.63 respectively. Different sizes, locations and fibrosis backgrounds had no effect on the elastic value and elastic ratio of liver tumors （ P ~0.05）. Conclusions Shear wave point quantification technology can help in differential diagnosing hepatic malignant tumor. Tumor＇s size, location and different fibrosis backgrounds have non-significant effect on the measurement of elastic value.

关 键 词：弹性成像技术 肝肿瘤 剪切波组织定量 

分 类 号：R735.7[医药卫生—肿瘤] R445.1[医药卫生—临床医学]