含氟羟基磷灰石涂层对正畸微种植体骨结合及周围炎的影响  

The effects of fluor-hydroxyapatite coating on the osseointegration and peri-implantitis of orthodontic micro-implants

作　　者：丁元圣[1] 赵玥[2] 郭睿[1] 曾娟[1] 赵刚[1] 

机构地区：[1]佳木斯大学口腔医学院口腔正畸科,154000 [2]佳木斯大学口腔医学院口腔儿童牙病科,154000

出　　处：《实用口腔医学杂志》2016年第5期624-626,共3页Journal of Practical Stomatology

基　　金：佳木斯大学自然科学项目(编号:JMSUJCMS2016-053)

摘　　要：目的:探讨含氟羟基磷灰石涂层(FHA)钛合金及钛合金正畸微种植体对骨结合及种植体周围炎的影响。方法:将微种植体植入兔下颌前磨牙区颊侧牙槽骨,扫描电镜观察骨结合状态,ELISA检测龈沟液中肿瘤坏死因子-α(TNF-α)含量。结果:FHA涂层组比钛合金组骨密度更致密,骨髓腔更小。炎症诱发前后钛合金组TNF-α水平较高,持续时间较长(P<0.05)。结论:FHA涂层钛合金微种植体的骨组织相容性较好,对种植体周围炎起到一定的抑制作用。Objective： To study the effects of fluor-hydroxyapatite （FHA） coating titanium alloy on the osseointegration and peri-implantitis of orthodontic micro-implant. Methods： Titanium of FHA alloy （FHA group） and titanium alloy（ control group） orthodontic microimplants were respectively planted into buccal alveolar bone in mandibular premolar area of rabbits. Scanning electron microscope was used to observe the osseointegration around the micro-implants. ELISA was employed to detect TNF-α in the gingival crevicular fluid around the implants. Results： The FHA-coating titanium alloy orthodontic micro-implants led to higher bone density, smaller marrow cavity, and lower TNF- α level and shorter lasting period of TNF- α over- expression than the controls （ P 〈 0.05 ）. Conclusion ： The FHA- coating titanium alloy orthodontic micro-implant has better histocompatibility and may inhibit peri-implantitis.

关 键 词：含氟羟基磷灰石涂层(FHA) 正畸微种植体 龈沟液 

分 类 号：R783.5[医药卫生—口腔医学]