血清SCC-Ag水平与宫颈鳞癌ⅠB1期病理特征的关系  

Relationship between Serum Levels of SCC-Ag and Pathological Features of Stage ⅠB1 Cervical Squamous Cell Carcinoma

作　　者：祝慧婷 刘程程[1] 梁美蓉[2] 刘晖[2] 江维[2] 曾四元[2] 

机构地区：[1]南昌大学研究生院医学部 [2]江西省妇幼保健院肿瘤科,南昌330006

出　　处：《实用临床医学（江西）》2016年第9期30-32,共3页Practical Clinical Medicine

摘　　要：目的探讨血清鳞状细胞癌抗原(squamous cell carcinoma antigen,SCC-Ag)水平与宫颈鳞癌ⅠB1期病理特征的关系。方法回顾性分析185例宫颈鳞癌ⅠB1期患者手术前后血清SCC-Ag水平与淋巴结转移、肌层浸润深度、间质侵犯的关系,并对其进行相关性分析。结果 185例患者有淋巴结转移、肌层浸润深度≥1/2、有间质侵犯的术前血清SCC-Ag水平均明显高于无淋巴结转移、肌层浸润深度<1/2、无间质侵犯(均P<0.05),术前血清SCC-Ag水平与淋巴结转移呈正相关(r=0.86,P<0.05)。结论宫颈鳞癌ⅠB1期患者术前血清SCC-Ag可用于评估淋巴结转移情况。Objective To discuss the relationship between serum levels of squamous cell carcinoma antigen（SCC-Ag）and pathological features of stageⅠB1cervical SCC.Methods The relationships of serum SCC-Ag levels to lymph node metastasis,myometrial invasion depth and stromal invasion were retrospectively analyzed in 185 patients with stageⅠB1cervical SCC.ResultsPreoperative levels of serum SCC-Ag in patients with lymph node metastasis,myometrial invasion depth≥1/2and stromal invasion were higher than those in patients with non-lymph node metastasis,myometrial invasion depth〈1/2and non-stromal invasion（P〈0.05）.Preoperative SCC-Ag levels were positively correlated with lymph node metastasis（r=0.86,P〈0.05）.ConclusionPreoperative serum levels of SCC-Ag can be used for the assessment of lymph node metastasis in patients with stageⅠB1cervical SCC.

关 键 词：宫颈鳞癌ⅠB1期 鳞状细胞癌抗原 血清 淋巴结转移 肌层浸润深度 间质侵犯 

分 类 号：R737.33[医药卫生—肿瘤] R446.1[医药卫生—临床医学]