细针吸取细胞学检查用于阴道残端结节的诊断研究  

Fine Needle Aspiration Cytology in Diagnosis of Vagina Stump Nodules After Total Hysterectomy

作　　者：王春丹[1] 王长亮[2] 董春鸽[1] 张春丽[1] 刘玉凤[1] 麻林爱[1] 

机构地区：[1]浙江中医药大学第一附属医院,浙江杭州310006 [2]浙江大学附属邵逸夫医院,浙江杭州310016

出　　处：《肿瘤学杂志》2016年第9期746-751,共6页Journal of Chinese Oncology

摘　　要：[目的]探讨阴道残端结节细针吸取细胞学检查(fine needle aspiration cytology,FNAC)的临床应用价值。[方法 ]选取115例阴道残端结节患者,随机分成两组,试验组68例阴道残端结节采用FNAC检查;对照组47例采用传统液基细胞学检查,两组患者均进行组织学结果对比研究,分析细胞形态特点与鉴别诊断,比较两种方法诊断的敏感性、特异性和符合率,并分析结节大小、肿瘤分期、首次根治及放化疗至复发的间隔时间与阳性率的关系。[结果]阴道残端结节FNAC检查作为阴道残端肿瘤复发诊断方法的敏感性为90.1%,符合率为92.6%,假阴性率9.8%,假阳性率为0,其中敏感性和假阴性结果显著优于传统液基细胞学方法(P<0.05)。[结论]阴道残端结节FNAC检查可以准确、微创地对阴道残端结节性质进行病理学诊断,具有较高的临床应用价值。[Objective] To evaluate the clinical application of fine needle aspiration cytology（FNAC） in the diagnosis of vaginal stump nodules after total hysterectomy. [Methods] One hundred and fifteen patients with vaginal stump nodules after total hysterectomy were randomly divided into two groups：68 cases in study group underwent FNAC,and 47 cases in control group received liquid-based cytology. The diagnostic sensitivity,specificity,and coincidence rate of two groups were compared. The relationship of tumor recurrence with tumor size,tumor stage,the duration of initial radical operation or chemotherapy was analyzed. [Results] The sensitivity of vaginal stump nodules FNAC in diagnosis of vaginal stump tumor recurrence was 90.1%,specificity was 100.0% and coincidence rate was 92.6%,which were significantly better than those of liquidbased cytology method（P〈0.05）. [Conclusion] FNAC can be used for pathological diagnosis of the recurrence of vaginal stump tumor after total hysterectomy,which has value of clinical application.

关 键 词：子宫切除术 阴道残端 细针吸取细胞学检查 病理学 

分 类 号：R737.3[医药卫生—肿瘤] R730.21[医药卫生—临床医学]