急性脑梗死合并阻塞性睡眠呼吸暂停低通气综合征患者认知功能的动态观察  

Dynamic observation of cognitive function in patients with acute cerebral infarction combined with obstructive sleep apnea hypopnea syndrome

作　　者：庾建英[1] 李妍慧[1] 付玉华[1] 

机构地区：[1]新疆维吾尔自治区人民医院北院急诊病房

出　　处：《实用老年医学》2016年第9期752-755,共4页Practical Geriatrics

摘　　要：目的探讨急性脑梗死合并不同程度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者认知功能、神经功能及日常生活能力的差异,为临床监测及干预治疗提供依据。方法收集我院2010年12月至2014年12月住院的急性脑梗死患者101例,其中急性脑梗死伴轻度OSAHS患者26例,急性脑梗死伴中度OSAHS患者23例,急性脑梗死伴重度OSAHS患者24例,单纯急性脑梗死患者28例。观察各组认知功能、神经功能、日常生活能力的变化。结果急性脑梗死合并中、重度OSAHS患者与单纯急性脑梗死患者在不同的时间段认知功能评分(Mo CA)、神经功能缺损评分(NIHSS)和日常生活能力评分(MBI)差异均有统计学意义(P<0.01),且急性脑梗死合并OSAHS程度越重,Mo CA评分和MBI评分越低,NIHSS评分越高。结论急性脑梗死合并OSAHS的患者,随着OSAHS程度的加重,认知功能障碍加重,且神经功能及日常生活能力恢复差,临床上应加强监测及干预治疗,尤其是急性脑梗死合并中度、重度OSAHS患者。Objective To explore the difference of cognitive function,nerve function and activity of daily living in the patients with acute cerebral infarction（ ACI） combined with different degrees of obstructive sleep apnea hypopnea syndrome（ OSAHS）. Methods 101 cases of ACI from December 2010 to December 2014 in our hospital were enrolled. There were26 cases with mild OSAHS,23 cases with moderate OSAHS,24 cases with severe OSAHS,and 28 cases were simple ACI.The cognitive function,nerve function,and activity of daily living of different groups were evaluated and compared. Results There were significant difference in the scores of Mo CA,NIHSS,and MBI between ACI combined with moderate and severe OSAHS group and simple ACI group（ P〈0. 01）. The ACI patients with more serious OSAHS,the scores of Mo CA and MBI were lower and the score of NIHSS was higer. Conclusions The damage of cognitive function,nerve function and activity of daily living in the patients with ACI combined with OSAHS may become more serious along with aggravation of OSAHS.

关 键 词：急性脑梗死 阻塞性睡眠呼吸暂停低通气综合征 认知功能 神经功能 日常生活能力 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R563[医药卫生—临床医学]