分化型甲状腺癌Galectin-3和人骨髓内皮细胞标志物表达及^(18)F-FDG显像的研究与应用  

Expression of Galectin-3 in Differentiated Thyroid Carcinoma and Human Bone Marrow Endothelial Cell Marker and Study and Application of the ^(18)F-Fluordeoxyglucose Imaging

作　　者：石野宽 游金辉[1] SHI Yekuan YOU Jinhui(Department of Nuclear Medicine, the Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Chin)

机构地区：[1]川北医学院附属医院核医学科,南充637000

出　　处：《生物医学工程学杂志》2016年第5期1020-1024,共5页Journal of Biomedical Engineering

基　　金：2014年南充市应用技术研究与开发资金项目(14A0041)资助

摘　　要：β-半乳糖结合蛋白(Galectin-3)和人骨髓内皮细胞标志物(HBME-1)在肿瘤的生长、转移中发挥着重要作用,是甲状腺癌的良好标志物。18氟-氟代脱氧葡萄糖(18F-FDG)正电子发射断层显像/计算机断层扫描(PET/CT)的应用提高了对甲状腺癌诊断的特异性和准确性。本文对分化型甲状腺癌中Galectin-3、HBME-1的表达及18 F-FDG显像在甲状腺癌中的研究与应用进行了综述。Galectin-3 and human bone marrow endothelial cell marker （HBME-1）, which play an important role in tumor growth and metastasis, are good markers for thyroid cancer. The diagnosis specificity and accuracy for thyroid cancers have been increased with the application of ^18F-fluordeoxyglucose （^18F-FDG） positron emission tomography/ computed tomography （PET/CT）. The value of Galectin-3, HBME-1 expression and ^18F-FDG imaging in differenti- ated thyroid carcinoma is reviewed in the present paper.

关 键 词：分化型甲状腺癌 半乳糖凝集素-3 人骨髓内皮细胞标记物 ^18氟-氟代脱氧葡萄糖 正电子发射断层显像/计算机断层扫描 

分 类 号：R736.1[医药卫生—肿瘤]