管状胃代食管术与全胃代食管术治疗食管癌的安全性与有效性对比  

Comparison of Safety and Efficacy of Gastric Tube and Whole Stomach Reconstruction in Surgery for Esophageal Cancer

作　　者：景瑞军[1] 李汉杰[1] 葛鹏[1] 王智[1] 陈鑫[1] 

机构地区：[1]西安医学院第二附属医院胸外科,陕西西安710038

出　　处：《现代生物医学进展》2016年第26期5127-5130,共4页Progress in Modern Biomedicine

摘　　要：目的:对比管状胃代食管术与全胃代食管术治疗食管癌的安全性与有效性。方法:2005年1月到2015年2月选择我院收治的100例食管癌患者,根据随机数字表法分为治疗组与对照组各50例,所有患者都行食管癌切除术,同时对照组给予全胃代食管手术,治疗组给予管状胃代食管术,对两组患者围手术指标、并发症及生活质量状况进行观察比较。结果:所有患者完成手术,治疗组的手术时间、术中出血量、术后住院时间、术后胃肠减压时间及术后闭式引流时间都明显少于对照组(P<0.05)。治疗组术后3个月反流性食管炎、胃排空障碍、胸胃综合征、吻合口狭窄、吻合口瘘等并发症发生情况明显少于对照组(P<0.05),日常生活、一般状况、治疗相关症状、社会影响、情感活动评分都明显高于对照组(P<0.05)。结论:相对于全胃代食管术,管状胃代食管术在治疗食管癌患者中的应用具有更好的安全性与有效性,值得进一步临床研究与推广。Objective： To compare the safety and efficacy compare of gastric tube and whole stomach reconstruction in surgery for esophageal cancer. Methods： From January 2005 to February 2015 in our hospital, 100 patients diagnosed esophageal cancer were selected and randomly equally divided into the treatment group and the control group. All the patients were given the esophageal cancer resection, while the patients in control group were give the whole stomach reconstruction surgery, and the patients in treatment group were received the gastric tube reconstruction surgery. Then perioperative indexes, complications and life quality were observed and compared of two groups. Results： All patients were completed the surgery, the operative time, blood loss, postoperative decompression time, postoperative close drainage time and postoperative hospital stay in the treatment group were significantly less than the control group （P 〈0.05）. The reflux esophagitis, gastric emptying, stomach chest syndrome, anastomotic stricture, fistula and other complications in the treatment group after postoperative 3 months were significantly less than that of the control group （P 〈0.05）. The daily living, general condition, treatment-related symptoms, and social impacts, emotional activity scores in the treatment group after postoperative 3 months were significantly higher than that of the control group （P 〈0.05）. Conclusions： Compared to the whole stomach reconstruction, the gastric tube reconstruction surgery has better safety and efficacy in the treatment of esophageal cancer, which is worthy of further clinical research and promotion.

关 键 词：食管癌 管状胃代食管术 全胃代食管术 并发症 生活质量 

分 类 号：R735.1[医药卫生—肿瘤]