紫外线对LASEK术后早期角膜Haze的影响  被引量:4

Effects of ultraviolet radiation on early corneal Haze after LASEK

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作  者:王晓雄[1] 曹婷[1] 邢怡桥[1] 

机构地区:[1]武汉大学人民医院眼科,湖北省武汉市430060

出  处:《眼科新进展》2016年第10期943-945,共3页Recent Advances in Ophthalmology

基  金:湖北省自然科学基金资助(编号:2012FFB04301)~~

摘  要:目的探讨紫外线暴露与LASEK术后早期角膜Haze形成的关系。方法选取2012年1月至2013年12月在武汉大学人民医院接受LASEK的近视患者199例(389眼),按照患者接受手术的时间分为两组:一组接受手术的月份为紫外线强度较弱的1月、2月、11月、12月,为低紫外线暴露组;另一组接受手术的月份为紫外线强度较强的5月、6月、7月、8月,为高紫外线暴露组。比较两组术后早期(术后3个月内)角膜Haze的发生情况。结果两组一般资料比较,高紫外线暴露组的切削光学区(5.6±0.5)mm大于低紫外线暴露组(5.5±0.5)mm,差异有统计学意义(t=-2.244,P=0.026),而两组性别、年龄、术前屈光度等效球镜、术前角膜中心厚度、切削深度、角膜切削率(术中角膜切削深度/术前角膜中心厚度)的差异均无统计学意义(均为P>0.05)。高紫外线暴露组术后角膜Haze达到0级、0.5级、1级、2级的比例分别为77.4%、12.3%、6.3%、4.0%,低紫外线暴露组的比例分别为86.9%、8.0%、4.4%、0.7%,差异有统计学意义(Z=-2.325,P=0.020),高紫外线暴露组患者的角膜Haze较重。术后角膜Haze达到2级的患者集中在高紫外线暴露组,手术月份集中在6月、7月、8月。结论环境中的高紫外线辐射可能促进LASEK术后早期角膜Haze的形成。Objectivc To investigate the correlation between the incidence of early corneal Haze after LASEK and ultraviolet radiation levels. Methods The study comprised 199 patients (389 eyes) who underwent LASEK surgery from January 2012 to December 2013 in Renmin Hospital of Wuhan University. The Patients were divided into two groups according to the months when they underwent LASEK surgery: a low ultravi- olet radiation group which was treated on January, February, November and December, and a high ultraviolet radiation group which was treated on May,June,July and August. The occurrence of the early corneal Haze after LASEK ( within 3 months) was com- pared between the two groups. Results The optical zone in the high ultraviolet radia- tion group was(5.5 ±0.5)mm,which was statistically larger than that in the low ultra- violet radiation group (5.5 ± 0.5 ) mm ( t = - 2.244,P = 0.025 ), but the difference on gen- der, age ,preoperative spherical equivalent, central corneal thickness, cutting depth, and cutting ratio between two groups was not statistically significant ( all P 〉 0.05 ). The proportions of eyes with early corneal Haze at grade 0,0. 5, 1 and 2 were 77. 4% , 12. 3% ,5.3% and 4.0% respectively in the high ultraviolet radiation group,and the pro- portions were 86.9% , 8.0% , 4.4% , 0.7% respectively in the low ultraviolet radiation group, there was statistical difference ( Z = - 2.325 ,P= 0.020). Most of the patients with corneal Haze of grade 2 were in the high ultraviolet radiation group and treated on June ,July and August. Conclusion High ultraviolet radiation in the environment may promote the formation of Haze in the early postoperative period of LASEK.

关 键 词:LASEK 紫外线 角膜 雾状混浊 

分 类 号:R772.2[医药卫生—眼科]

 

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