近视发生时间与反应性AC/A相关性研究  

Relationship between response accommodative convergence/accommodation(AC/A) ratio and onset of myopia

作　　者：王婷[1] 赵堪兴[1] 李丽华[1] 王蕊[1] 程文博[1] 

机构地区：[1]天津市眼科医院、天津市眼科研究所,天津市300020

出　　处：《眼科新进展》2016年第10期975-978,共4页Recent Advances in Ophthalmology

摘　　要：目的研究近视者对于近距离目标物的调节反应和集合反应与近视的发生时间是否有明确的联系,以及使用正、负镜片作为调节刺激的梯度法测得的反应性调节性集合与调节比值(AC/A)和刺激性AC/A的值是否有差异。方法 92位志愿者参加本研究。将受试者分为正视组22例、早发性近视(近视发生在15岁之前)组44例和迟发性近视(近视发生在15岁之后)组26例。分别用+1.00 D和-1.00 D的镜片作为调节刺激,测量计算三组受试者的AC/A。结果不同组别的调节滞后量、调节性集合和刺激性AC/A无论在正镜片还是在负镜片刺激下差异均无统计学意义(均为P>0.05);但不同组别在正、负镜片刺激下的反应性AC/A比较,差异均有统计学意义(P=0.019、0.000)。正视组和早发性近视组在正镜片刺激下所得的刺激性AC/A和反应性AC/A的差异均有统计学意义(P=0.000、0.000),在负镜片刺激下所得的刺激性AC/A和反应性AC/A的差异无统计学意义(P>0.05);迟发性近视组在正、负镜片刺激下所得的刺激性AC/A和反应性AC/A的差异均有统计学意义(P=0.002、0.006)。结论无论是早发性近视者还是迟发性近视者,其反应性AC/A均高于正视者;不同性质的调节刺激测出的AC/A也有差别,与受试者的屈光状态类型有关。Objective To examine whether the response AC/A ratio （the a- mount of accommodative convergence perunit of accommodative response ） and the stimulus AC/A ratio varies as a function of refractive error, age and different tecniques. Methods Ninety-two volunteers were enrolled in this study, and divided into emme- tropia group, early-onset myopia （myopia onset prior to 15 years of age） group and late-onset myopia （onset 15 years or later） group. The response AC/A ratio, stimulus AC/A ratio with ＋ 1.00 D add and - 1.00 D add over the corrective lens were meas- ured. Results There was no statistical difference among the three different groups in the lag of accommodation, the accommodative convergence and the stimulus AC/A ratio （ all P 〉 0.05 ）, but the response AC/A ratio shows a statistical difference among the groups（P=O. 019,0.000）. Different techniques showed different influence on the AC/A ratio. There were statistical differences in the stimulus and response AC/A ratio in the emmetropia group and early-onset myopia group under ＋ 1.00 D add over the corrective lens （P =0.000,0.000） ,but there was no statistical difference under -1.00 D add over the corrective lens （P 〉 0. 05 ）. There were statistical differences in the stimulus and re- sponse AC/A ratio in the late-onset myopia group under ＋ 1.00 D and - 1.00 D add over the corrective lens （P = 0.002,0. 006）. Conclusion The myopia exhibits a significantly higher response AC/A ratio than the emmetropia. The AC/A ratio show difference between different techniques＇ results, and it depend on the type of myopia.

关 键 词：近视 反应性AC/A 刺激性AC/A 

分 类 号：R778.1[医药卫生—眼科]