肠道菌群失衡与肠易激综合征  

Irritable bowel syndrome and gut microbiota dysbiosis

作　　者：章菲菲[1] ZHANG Feifei(Department of Gastroenterology, Shanghai Armed Police Corps Hospital, Shanghai 201103, China)

机构地区：[1]武警上海总队医院消化科,上海201103

出　　处：《上海医药》2016年第19期3-8,共6页Shanghai Medical & Pharmaceutical Journal

摘　　要：肠易激综合征(irritable bowel syndrome,IBS)是一种常见的功能性胃肠道疾病,其发病机制目前尚不完全清楚,但有越来越多的证据表明IBS可能与肠道菌群谱的改变有关。本文就IBS患者存在的结肠菌群失衡、小肠细菌过度生长及它们可能的致病机制,以及干预肠道菌群失衡等的治疗手段作一综述。Irritable bowel syndrome （IBS） is one the most common diseases with functional dyspepsia while the mechanism of its pathogenesis is still obscure. However, more and more evidences have demonstrated that IBS may be closely associated with the alteration of the gut microbiota. This review discusses gut microbiota dysbiosis in colon, small intestinal bacterial overgrowth and the possible mechanisms of their pathogenesis as well as the treatment methods for gut microbiota modulation.

关 键 词：肠易激综合征 肠道菌群失衡 低度黏膜炎症反应 

分 类 号：R574.4[医药卫生—消化系统]