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机构地区:[1]北京大学第一医院中医中西医结合科,北京100034
出 处:《医学综述》2016年第19期3854-3857,共4页Medical Recapitulate
摘 要:非酒精性脂肪性肝病(NAFLD)是我国常见的慢性肝病之一,其发病与胰岛素抵抗及人群易患性关系密切,常与心血管疾病及糖尿病等代谢性疾病并发。该病在中医体质分类中以痰湿质居多,患者多肥胖,多伴有脾胃功能失调、内分泌失调等。中医药在治疗痰湿质NAFLD方面有着广泛的应用,多种药物及非药物疗法对该病均具有显著疗效。深入研究痰湿质NAFLD的发病机制,并建立完善的临床疗效评价标准,将有助于中医药在临床的规范化应用,正确指导临床用药。As one of the common chronic liver diseases in China, non-alcoholic fatty liver disease (NAFLD) is commonly accompanied with cardiovascular and metabolic diseases such as diabetes. The occurrence of the disease is closely related to insulin resistance and genetic predisposition. In traditional Chinese medicine (TCM) syndrome classification, most NAFLD patients are phlegm dampness type, with clinical manifestations of obesity, endocrine dyscrasia, disorder of spleen and stomach. TCM has been widely applied in NAFLD of phlegm-dampness type, with obvious therapeutic effects of pharmacotherapy and nou-pharmacotherapy. Lucubrating the pathogenesis of NAFLD of phlegm-dampness type and establishing thorough effect evaluation criterion will be helpful in the standardized application of TCM, to guide the more reasonable clinical prescription.
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