VP-16偶联血小板治疗难治型 ITP 的研究  

Study of Treatment of Refractory Idipathic Thrombocytopentic Purpura with VP-16-binding Platelets

作　　者：丁子清[1] 胡兆平[1] 朱新友[1] 陈家萍[1] 潘理明[2] 朱微波[2] 宋海波[2] 王祖贻[2] 

机构地区：[1]安徽省立医院输血科 [2]安徽省立医院血液病科

出　　处：《中国输血杂志》1991年第3期115-116,114,共3页Chinese Journal of Blood Transfusion

摘　　要：本文应用固相血小板免疫血清学试验(SPISA)为难治型特发性血小板减少性紫癜(ITP)病人筛选不配合的供血者血小板,用该血小板载体与 VP-16(足叶乙甙)偶联,并输给5例难治型 ITP 病人。5例治疗均有效,其中4例完全缓解,显示了临床上的治疗价值。A technique of solid-phase pla-telet immunoserological assay wasused to select unsuitable plateletdonors for patients with refractory (?)diopathic thrombocytopenic purpura(RITP).The unsuitable plateletswere used as carriers to bind with VP-16 (Etoposide),and then wesetransfused into5patients with RITP.All the cases were benefited by sucha therapy,and 4 of them were cured.indicating that the therapy has itscurative value in clinical practice.(Original article on page 115)

关 键 词：血小板 ITP 紫癜 

分 类 号：R554.605[医药卫生—血液循环系统疾病]