功能性消化不良不同亚型患者心理因素的比较研究  

Comparative Study on Psychological Factors in Subgroups of Patients with Functional Dyspepsia

作　　者：张琴[1] 贺国斌[2] 刘平[1] 向佳[1] 向霞[1] ZHANG Qin HE Guobin LIU Ping XIANG Jia XIANG Xia(Department of Gastroenterology, People＇ s Hospital of Xuanhan County, Dazhou, Sichuan Province （ 636150 Department of Gastroenterology, the Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan Province)

机构地区：[1]宣汉县人民医院消化内科,636150 [2]川北医学院附属医院消化内科

出　　处：《胃肠病学》2016年第9期554-556,共3页Chinese Journal of Gastroenterology

摘　　要：背景:焦虑、抑郁、躯体化是影响功能性消化不良(FD)患者生活质量的重要因素,但与FD各亚型之间的关系尚不完全清楚。目的:探索焦虑、抑郁和躯体化对FD各亚型患者的影响。方法:应用焦虑自评量表(GAD-7)、抑郁自评量表(PHQ-9)、躯体化症状自评量表(PHQ-15)、悉尼消化不良指数简表(NDI)和消化不良症状严重度量表(DSS)分别评估223例FD患者的焦虑、抑郁、躯体化、生活质量和消化不良严重度,并分析焦虑、抑郁、躯体化对FD各亚型生活质量和消化不良的影响。结果:EPS、PDS和EPS与PDS重叠组的GAD-7、PHQ-9、PHQ-15、NDI、DSS评分相比差异有统计学意义(P<0.05)。FD各亚型患者的生活质量与焦虑、抑郁和躯体化均相关(P<0.05),而消化不良严重度仅与躯体化相关(P<0.05)。抑郁和躯体化是影响FD各亚型患者生活质量的因素(P<0.05),躯体化是影响各亚型患者消化不良的因素(P<0.05)。结论:EPS与PDS症状重叠患者的焦虑、抑郁、躯体化较EPS、PDS患者严重,对生活质量和消化不良的影响亦更大。Anxiety, depression and somatization are important influencing factors of quality of life in patients with functional dyspepsia （ FD ） , but the relationship with subgroups of FD remains not fully clear. Aims ： To explore the influence of anxiety, depression and somatization on subgroups of FD patients. Methods： Generalized Anxiety Disorder-7 （GAD-7）, Patient Health Questionnaire-9 （PHQ-9） , Patient Health Questionnaire-15 （ PHQ-15 ）, Nepean Dyspepsia Index （NDI） and Dyspepsia Symptoms Score （DSS） were used to evaluate anxiety, depression, somatization, quality of life and dyspepsia of 223 FD patients, respectively. The influences of anxiety, depression and somatization on quality of life and dyspepsia in subgroups of FD were analyzed. Results： Significant differences in score of GAD-7, PHQ-9, PHQ-15, NDI, DSS were tound among EPS group, PDS group and EPS-PDS overlapping group （P 〈 0.05）. Quality of life in subgroups of FD was correlated with anxiety, depression and somatization （ P 〈 0.05 ） , and dyspepsia was correlated with somatization （ P 〈 0.05 ）. Depression and somatization were the determinants of quality of life in subgroups of FD patients （P 〈0.05）, and somatization was the determinant of dyspepsia in subgroups of FD patients （P 〈 0. 05 ）. Conclusions： Anxiety, depression and somatization in EPS-PDS overlapping patients are more severe than those in EPS and PDS patients, and the influence of these three risk factors on quality of life and dyspepsia are more severe.

关 键 词：功能性消化不良 焦虑 抑郁 躯体化 

分 类 号：R57[医药卫生—消化系统]