肠易激综合征临床诊断的潜在生物学标记物  

Potential Biomarkers for Clinical Diagnosis of Irritable Bowel Syndrome

作　　者：罗和生[1] 任海霞[1] 张法灿[2] 梁列新[2] 张国[2] LUO Hesheng REN Haixia ZHANG Facan LIANG Liexin ZHANG Guo(Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan （430060 Department of Gastroenterology, the People＇s Hospital of Guangxi Zhuang Autonomous Region, Nanning)

机构地区：[1]武汉大学人民医院消化内科,430060 [2]广西壮族自治区人民医院消化内科

出　　处：《胃肠病学》2016年第9期565-568,共4页Chinese Journal of Gastroenterology

摘　　要：肠易激综合征(IBS)是一种以腹痛或腹部不适,伴排便习惯或粪便性状改变为主要临床特征的功能性肠病。IBS的病因和发病机制尚未完全明确,使诊断存在一定困难。目前IBS的诊断主要是基于临床症状,易漏诊、误诊。随着基础和临床研究的深入,一些潜在的IBS相关生物学标记物受到广泛关注。本文就IBS临床诊断的潜在生物学标记物作一综述。Irritable bowel syndrome （IBS） is a functional intestinal disease with the main clinical manifestations of abdominal pain/discomfort and changes of bowel habit and fecal character. The etiology and pathogenic mechanism of IBS are not fully clarified, which makes difficulties in the diagnosis. Currently, the diagnosis of IBS is mainly based on clinical symptoms, and missed diagnosis and misdiagnosis can occur easily. With the advances in basic and clinical research, various potential biomarkers of IBS have attracted more and more attention. This article reviewed the potential biomarkers for clinical diagnosis of IBS.

关 键 词：肠易激综合征 诊断 鉴别 生物学标记 内分泌细胞 

分 类 号：R574.4[医药卫生—消化系统]