乏脂肪型肾错构瘤患者的CT灌注参数与肾功能生化检测指标的相关性  

The correlation between renal function biochemical index and CT perfusion parameters in the lack of fat-type renal angiomyolipoma patients

作　　者：张旭辉[1] 陈晓荣[1] 张珊珊[1] 

机构地区：[1]湖北医药学院附属东风医院影像科,湖北十堰442008

出　　处：《现代肿瘤医学》2016年第22期3585-3588,共4页Journal of Modern Oncology

基　　金：十堰市科学技术研究项目(编号:14Y52)

摘　　要：目的:探讨乏脂肪型肾错构瘤患者的CT灌注参数与肾功能生化检测指标的相关性。方法:选择在本院诊治的乏脂肪型肾错构瘤患者34例作为观察组,同期选择在我院进行体检的健康人34例作为对照组,两组都进行肾功能相关生化检测指标(BUN、Scr、TG、TC、HDL-C、LDL-C)的检测与CT灌注参数(BV、BF、PS、MTT)检测,同时进行相关性分析。结果:观察组的血清BUN、Scr、TG、TC和HDL-C值明显高于对照组,而LDL-C值明显低于对照组,对比差异都有统计学意义(P<0.05)。观察组肾皮质的BV、BF、PS值明显低于对照组,而MTT值明显高于对照组,对比差异都有统计学意义(P<0.05)。乏脂肪型肾错构瘤发生的主要危险因素包括BV、PS、BUN与TC等(P<0.05);Pearson相关系数分析显示乏脂肪型肾错构瘤患者的BV、BF、PS与BUN、TC存在明显的负相关性(P<0.05),而MTT与BUN、TC存在明显的正相关性(P<0.05)。结论:乏脂肪型肾错构瘤患者存在明显的肾功能与血脂等生化指标异常,同时CT灌注参数也处于异常情况,可参与到乏脂肪型肾错构瘤的形成,存在一定的相关性,在临床上有很好的应用价值。Objective： To investigate the correlation between renal function biochemical indexes and CT perfusion parameters in the lack of fat- type renal angiomyolipoma patients. Methods： Selected 34 lack fat type renal angiomyolipoma patients 34 as the observation group,and 34 healthy people at the same period as the control group. Both groups were detected for the renal function biochemical index（ BUN,Scr,TG,TC,HDL- C,LDL- C） and CT perfusion parameters（ BV,BF,PS,MTT）. Results： The serum BUN,Scr,TG,TC and HDL- C in the observation group were significantly higher than the control group,while the LDL- C values were significantly lower than the control group. BV,BF,PS values in the observation group were significantly less than the control group,while the MTT values were significantly higher that compared the differences were all statistically significant comparison（ P 〈0. 05）. The main risk factors for the lack of fat type of renal angiomyolipoma included BV,PS,BUN and TC（ P 〈0. 05）. Pearson correlation analysis showed that the BV,BF,PS were significant negatively correlated to the BUN,TC in the lack of fat type of renal patients（ P 〈0. 05）,and MTT were significant positive correlated to the BUN,TC（ P 〈0. 05）. Conclusion： The lack of fat- type patients with renal angiomyolipoma has biochemical abnormalities of renal function and lipid biochemical abnormalities,while CT perfusion parameters is in an abnormal situation,that may participate in the formation of the disease and have certain correlation.

关 键 词：乏脂肪型肾错构瘤 肾功能 血脂 CT灌注参数 相关性 

分 类 号：R737.11[医药卫生—肿瘤]