化痰通络汤治疗急性脑梗死的临床观察  

The Clinical Study on the Influence of Huatan Tongluo Decoction on Homocysteine in Patients with Acute Cerebral Infarction

作　　者：唐世球[1] 杨辉[1] 周丽华[1] 刘诚[1] 杨可[1] 任明[1] 王慧娟[1] TANG Shiqiu YANG Hui ZHOU Lihua et al(Huaibei Hospital of Traditional Chinese Medicine ,A nhui , Huaibei 235000, China)

机构地区：[1]安徽省淮北市中医医院,安徽淮北235000

出　　处：《中国中医急症》2016年第10期1973-1975,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：2014年度安徽省卫生计生委中医药科研课题(2014zy71)

摘　　要：目的观察化痰通络汤对急性脑梗死患者血同型半胱氨酸的影响及临床疗效。方法 120例患者随机分为治疗组和对照组两组,各60例。对照组采用西医常规治疗方法,治疗组在对照组基础上加用化痰通络汤,3周后评定临床疗效。比较两组治疗前后血同型半胱氨酸水平、神经功能缺损评分及中医症候积分。结果治疗组总有效率85.00%优于对照组的75.00%(P<0.01)。两组治疗前后中医证候积分与治疗前比较,均改善(P<0.01或P<0.05),且治疗组中医证候积分改善优于对照组(P<0.01或P<0.05)。两组治疗后同型半胱氨酸含量和临床神经功能缺损评分与治疗前比较均降低(均P<0.05),且治疗组同型半胱氨酸含量和临床神经功能缺损评分均低于对照组(均P<0.05)。结论化痰通络汤能降低急性脑梗死患者血同型半胱氨酸水平,提高临床疗效,可用于急性脑梗死的防治。Objective： To observe the effect of Huatan Tongluo Decoction on homocysteine in patients of acute cerebral infarction and its clinical efficacy. Methods： 120 eligible patients of acute cerebral infarction were re- cruited in this study. All the cases were randomly divided into study group （60 cases） and control group （60 cases）. The study group were treated with Huatan Tongluo Decoction and routine western medicine therapy, while the control group were treated with routine western medicine therapy only. Evaluating the curative effect 3 week later, the Homocysteine level,the Neural function and the TCM syndrome score before and after treatment between the two groups were compared. Results： The study group was better than the control group in the clinical efficacy and in regulating the Homocysteine level （P〈 0.05 or P〈 0.01）. Conclusion： Huatan Tongluo Decoction reduces the Homocysteine level and improves the clinical treatment effect of cerebral infarction and can be used for the prevention and treatment of acute cerebral infarction.

关 键 词：急性脑梗死 化痰通络汤 同型半胱氨酸 

分 类 号：R743.9[医药卫生—神经病学与精神病学]