视觉电生理技术在青光眼早期诊断中的意义  

Significance of visual electrophysiological techniques in the early diagnosis of glaucoma

作　　者：张晓培[1] 苏秀明 姚牧笛 蒋沁[1] 曹国凡[1] 

机构地区：[1]南京医科大学附属眼科医院,中国江苏省南京市210000

出　　处：《国际眼科杂志》2016年第11期2044-2047,共4页International Eye Science

摘　　要：青光眼是一组威胁和损害视神经及其视觉通路,最终导致视觉功能损害的疾病。青光眼视神经损害以视网膜神经节细胞(retinal ganglion cells,RGCs)及其轴突数目进行性丢失、视盘凹陷、视野缺损为特征。静态自动视野计检查是评估青光眼病程进展的金标准,但其结果往往受到患者主观因素的限制。近年来视觉电生理技术飞速发展,虽还不能代替传统的视野检查,但作为补充,其能在青光眼视野缺损前即出现振幅及潜伏期的改变,为早期青光眼的诊断提供了新的参考思路。本文主要对三种特殊类型的视网膜电图以及多焦视觉诱发电位在青光眼早期诊断中的意义进行综述。Glaucoma is a group of diseases which can threaten and damage the optic nerve and its visual pathway, leading to visual impairment as a result. Glaucomatous optic neuropathy is a chronic disease accompanied by apoptosis of retinal ganglion cells （ RGCs ） , visual field defect and cupping of optic nerve head. The gold standard in functional glaucoma evaluation is standard automated perimetry （ SAP） , but it is often limited to the subjective feelings of the patients. Still, visual electrophysiological techniques cannot replace the conventional inspection, but with its rapid development, it has provided a new strategy for the early diagnosis of glaucoma as a supplement because it can show changes in amplitude and latency before visual field defect. Here we review three special electroretinograms and multifocal focal visually evoked potentials in the early diagnosis of glaucoma.

关 键 词：早期青光眼 图形视网膜电图 明视负波反应 多焦视网膜电图 多焦视觉诱发电位 

分 类 号：R775[医药卫生—眼科]