内镜超声对胰腺神经内分泌肿瘤的诊断价值研究  

The diagnostic value of endoscopic ultrasonography for pancreatic neuroendocrine tumors

作　　者：刘渊[1] 杨秀疆[1] 孙波[1] 张文明[1] 张召珍[1] 贺益萍[1] 

机构地区：[1]复旦大学附属肿瘤医院内镜科 复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中华消化内镜杂志》2016年第10期680-683,共4页Chinese Journal of Digestive Endoscopy

摘　　要：目的通过与CT、B超、MRI及PET/CT进行比较，评估EUS对胰腺神经内分泌瘤（pNETs）的诊断价值。方法2012年7月至2016年3月，复旦大学附属肿瘤医院行EUS检查且病理确诊的70例pNETs患者（77个病灶）纳入回顾性研究，并对其中有外科手术病理的53例患者（60个病灶）的手术前EUS、B超、CT、MRI、PET/CT检查结果进行统计分析。结果EUS共检出76个病灶，当中32个〈2 cm的病灶使用了高清精细放大功能，49个病灶获得了符合质量的弹性成像图，42个实性病变或实性成分加测了精细血流，6例采用了3D成像功能。pNETs的EUS、B超、CT、MRI、PET/CT检出率分别为98.33%（59/60）、61.11%（33/54）、89.47%（51/57）、76.00%（19/25）、78.38%（29/37），其中〈2 cm病灶的检出率分别为96.30%（26/27）、47.83%（11/23）、76.00%（19/25）、54.55%（6/11）、58.82%（10/17）；pNETs病变部位的EUS、B超、CT、MRI、PET/CT判断准确率分别为91.67%（55/60）、51.85%（28/54）、80.70%（46/57）、72.00%（18/25）、75.68%（28/37）。结论通过应用精细血流、高清精细放大及弹性成像等功能，EUS对于pNETs尤其是〈2 cm的pNETs的诊断较传统影像学方法更有优势。Objective To study the diagnostic value of endoscopic uhrasonography （EUS）for pan- creatic neuroendocrine tumors （pNETs） by comparing EUS with computed tomography （CT）, ultrasonography, magnetic resonance imaging （MRI） and positron emission tomography/computed tomography （PET/CT）. Methods Data of 70 pNETs cases （a total of 77 lesions） confirmed by pathological diagnosis from July 2012 to March 2016 in Shanghai Cancer Center of the Fudan University were retrospectively stud- ied. Among the cases, 53 cases （a total of 60 lesions） were confirmed by surgical pathology and their results of EUS, abdominal ultrasonography, CT, MRI and PET/CT were compared before surgery. Results A total of 76 lesions were detected by EUS, in which 32 lesions less than 2 cm were tested by HI ZOOM high defini- tion amplification, qualified elastography images of 49 lesions were obtained, 42 solid lesions or solid components were also tested by Fine Flow, and 6 cases were tested by 3D imaging. Diagnostic rates of lesions by EUS, uhrasonography, CT, MRI and PET/CT were 98. 33% （59/60）, 61.11%（33/54）, 89. 47%（51/57）, 76. 00%（19/25） and 78.38%（29/37）, respectively. For lesions less than 2 cm, diagnostic rates by these ex- aminations were 96. 30% （ 26/27 ）, 47. 83% （ 11/23 ）, 76. 00% （ 19/25 ）, 54. 55% （ 6/11 ） and 58. 82% （10/17）, respectively. Accuracy rates of EUS, ultrasonography, CT, MRI and PET/CT in the location of these lesions were 91.67% （55/60）, 51.85% （28/54）, 80. 70% （46/57）, 72. 00% （18/25） and 75.68% （28/37）, respectively. Conclusion Combined with Fine Flow, HI ZOOM high definition amplification and elastography, EUS is superior to standard imaging for pNETs, especially for lesions less than 2 cm.

关 键 词：诊断价值 神经内分泌肿瘤 内镜超声 胰腺 PET/CT pNETs 神经内分泌瘤 附属肿瘤医院 

分 类 号：R735.9[医药卫生—肿瘤]