香元消痔巴布贴的质量标准研究  

Studies on quality control standard of Xiangyuan Xiaozhi cataplasm

作　　者：李文兵[1] 王洛临[1] 李智勇[1] 张诚光[1] 范宋玲[1] 

机构地区：[1]广东省第二中医院,广东广州510095

出　　处：《中药与临床》2016年第3期36-38,共3页Pharmacy and Clinics of Chinese Materia Medica

基　　金：广东省中医药局立项资助科研课题(编号:20131117)

摘　　要：目的：研究香元消痔巴布贴的质量控制标准。方法：采用薄层色谱法对制剂中地榆、黄柏进行定性鉴别,并用高效液相色谱法对制剂中的主药地榆进行含量测定。结果：薄层色谱斑点清晰,阴性对照无干扰;没食子酸在8.34~83.40ng之间成良好的线性关系,平均回收率为99.14%,RSD为1.06%（n=6）。结论：该法灵敏、简便、准确和重复性好,可作为该制剂的质量控制标准。Objective： To study quality control standard of Xiangyuan Xiaozhi cataplasm. Method： Diyu and Huangbo in preparation were identified by TLC. The content of Diyu, the main active medicine in cataplasm was determined by HPLC. Result： The TLC spots were clear and negative control showed no interference. Linearity was found in the range of 8.34 - 83.40 ng for gallic acid with average recovery of 99.14% （RSD=1.06%, n=6）. Conclusion： The method is sensitive, simple with good precise and reproducible, and can be used for the quality control of the cataplasm.

关 键 词：香元消痔巴布贴 质量标准 高效液相色谱法 没食子酸 

分 类 号：R284.1[医药卫生—中药学]