乳腺癌术后预防性使用抗生素与术后伤口感染的相关性分析  

Correlation analysis of postoperative prophylactic antibiotics and surgical site infection rates after breast cancer surgery

作　　者：郭宁[1] 高文[1] 李彩霞[1] 

机构地区：[1]天津市第四中心医院两腺科,天津300000

出　　处：《中国生化药物杂志》2016年第8期133-135,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探讨乳腺癌患者术后预防性使用抗生素与术后伤口发生感染机率的关系。方法回顾性分析了2007年3月~2016年3月天津市第四中心医院两腺科单纯术前预防性使用抗生素的267例患者作为对照组,以术前、术后均预防性使用抗生素的117例患者作为研究组。观察手术部位伤口感染率。结果研究组和对照组在30天之内手术部位伤口感染发生率以及在任何时间手术部位伤口感染发生率均无统计学差异;研究组＋术后引流和对照组＋术后引流在30天之内手术部位伤口感染发生率以及在任何时间手术部位伤口感染发生率均无统计学差异。结论乳腺癌患者术后预防性使用抗生素与术后伤口感染的发生无关。Objective To explore the relationship between the postoperative prophylactic antibiotics and surgical site infection rates after breast cancer surgery. Methods Retrospective review of patients with breast surgical procedures between March 2007 to March 2016 were included,267 cases only preoperative antibiotic prophylaxis as control group,and 117 cases of preoperative and postoperative prophylactic antibiotics as research group. The surgical site infection（ SSI） rates were compared. Results There was no statistically significant association between research groups and control group of SSI rates for both a 30-day postoperative period and beyond. Further,There was also no statistically significant association between research groups with drains and control group with drains of SSI rates for both a 30-day postoperative period and beyond. Conclusion There is no significant relationship between postoperative prophylactic antibiotics and surgical site infection rates after breast cancer surgery.

关 键 词：乳腺癌 预防性使用抗生素 伤口感染 

分 类 号：R737.9[医药卫生—肿瘤]