基因与缺血性脑卒中关系的研究进展  

Research progress on the relationship between gene and ischemic stroke

作　　者：王思洋[1] 邓本强[1] WANG Si-yang DENG Ben-qiang(Stroke center,Changhai Hospital,Second Military Medical University,Shanghai 200433,Chin)

机构地区：[1]第二军医大学长海医院脑血管病中心,上海200433

出　　处：《第二军医大学学报》2016年第10期1226-1229,共4页Academic Journal of Second Military Medical University

基　　金：国家自然科学基金(81270756)~~

摘　　要：近年来,由于基因学研究的不断发展,研究者们越来越多地从分子水平探索卒中的遗传学基础。相关研究将对某些由单基因所致卒中的临床诊疗有着至关重要的影响,甚至有可能在不久的将来为这些患者带来革命性的治疗措施。本综述将对缺血性脑卒中基因遗传学的研究现状进行总结,为临床医生在诊疗工作中更好地运用这些知识提供指导。Recent advances in genomics have allowed us to begin addressing the genetic basis of stroke at molecular level. These advances are especially important for clinical diagnosis and therapy of stroke caused by monogenic variation, and they may even lead to a revolutionary treatment for these patients. In this review, we summarized the current status of genetic research in ischemic stroke, hoping to provide guidance for clinicians in clinical practice.

关 键 词：脑梗死 变异(遗传学) 遗传多态现象 遗传药理学 

分 类 号：R743.33[医药卫生—神经病学与精神病学]