Kleine-Levin综合征6例临床分析及文献复习  

Kleine-Levin syndrome: Clinical analysis in 6 case with literature review

作　　者：陈珉 傅建梅 

机构地区：[1]莆田市第一医院神经内科,福建莆田351100

出　　处：《皖南医学院学报》2016年第5期476-478,共3页Journal of Wannan Medical College

摘　　要：目的:探讨Kleine-Levin综合征(KLS)的临床特点。方法:回顾性分析6例KLS患者的临床表现、辅助检查结果并复习文献,总结KLS的临床特点。结果:本组6例患者以周期性发作性嗜睡、病理性贪食、精神行为异常为主要特点,辅助检查无明显异常。结论:KLS临床少见,以周期性发作性嗜睡、病理性贪食、精神行为异常为主要特点,病因不明,中枢神经兴奋剂、心境稳定剂及部分抗癫痫药物有一定疗效,预后良好。Objective： To analyze the clinical features of Kleine-Levin syndrome（ KLS）.Methods： Retrospective analysis was performed in 6 cases of KLS regarding its clinical pictures,findings of supplemental examinations.The literatures associated with KLS were reviewed and the clinical features were analyzed.Results： Clinical symptoms of KLS was characterized by periodic paroxysmal drowsiness,pathological adephagia and mental disorder,yet supplemental examination revealed no obvious abnormityies.Conclusion： KLS is a rare disease in clinic characterized by periodic paroxysmal drowsiness,pathological adephagia and mental disorder.The etiology for KLS remains unclear,however,central verve stimulant,mood stabilizer and certain antiepileptic drugs can be curative effect and lead to better prognosis for this condition.

关 键 词：KLEINE-LEVIN综合征 嗜睡 贪食 

分 类 号：R749.1[医药卫生—神经病学与精神病学]