社区老人代谢综合征伴发抑郁障碍3年发展趋势流行病学调查  

The incidence of metabolic syndrome complicated with major depressive disorder among the old population from the community: a three-year epidemiological research

作　　者：胡承平[1] 瞿正万[1] 孙喜蓉[1] 江琦[1] 傅红梅[1] 袁杰[1] 杨振东[1] 张洁[1] 陆伟[1] 秦金[1] 戴婧[1] 

机构地区：[1]上海市浦东新区精神卫生中心,200124

出　　处：《临床精神医学杂志》2016年第5期310-313,共4页Journal of Clinical Psychiatry

摘　　要：目的:探索社区老人抑郁障碍与代谢综合征间的发生发展关系。方法:采用分层随机抽样法,对上海浦东新区>55岁的老年人进行调查,并在3年后对上述老人进行复查。以DSM-Ⅳ轴Ⅰ障碍定式临床检查患者版本为调查诊断工具,以内科诊断结果为代谢性疾病诊断依据。分析入组者抑郁障碍及代谢性疾病的患病率和易感因素。结果:调查第1年抑郁障碍发生率为16.76%,第3年为17.61%;调查第1年重症抑郁发生率为2.77%、亚临床抑郁发作2.82%、轻度抑郁发作3.99%、恶劣心境7.18%;与第3年比较均差异无统计学意义(P>0.05)。调查第1年代谢综合征患病率为56.25%、其中高血压为50.41%、糖尿病14.38%及高脂血症8.34%,与第3年比较均差异无统计学意义(P>0.05);代谢综合征与抑郁障碍共病率为23.72%,糖尿病与抑郁障碍共病率最高(52.32%),同时患有3种代谢性疾病者其与抑郁障碍的共病率为70.49%,明显高于患有2种、1种及无代谢性疾病者(P<0.05)。结论:3年内老年人MS与抑郁障碍的发生发展趋势相对平稳。Objective： To investigate the incidence of metabolic syndrome complicated with major de- pressive disorder among the elder. Method：Stratified random sampling was used to choose the subjects. The structured clinical interview for DSM-Ⅳ-TR Axis Ⅰ disorders-patient edition（SCID-I/P） was used as a standard to diagnose major depressive disorder. The diagnosis of metabolic syndrome was based on the opinions from de- partment of medicine. Results：The incidence of major depressive disorder was 16.76% according to the in- vestigation in the first year,and 17.61% in the third year. The incidence of major depression was 2.77% ,sub- clinical depression was 2.82% ,mild depression was 3.99% ,dysthymia was 7.18% in the first year,There were no significant differences from those in the third year （ P 〉 0.05 ）. The incidence of metabolic syndrome was 56.25% ,hypertension was 50.41%, diabetes was 14.38% and hyperlipidemia was 8.34% in the first year. There were no significant differences from those in the third year（P 〉0. 05）. The incidence of metabolic syn- drome complicated with major depressive disorder was 56.25%. The patients with diabetes had the highest sus- ceptibility of depression（52.32% ）. The patients with these three diseases were much easier to get depression （70.49%） compared with the patients who only had two, one or none of these diseases （ P 〈 0.05 ）. Conclusion：The incidence of major depressive disorder among the elder was relatively stable in three years.

关 键 词：老年人 抑郁障碍 代谢综合征 流行病学 

分 类 号：R749.4[医药卫生—神经病学与精神病学]