显微镜下单鼻腔经蝶垂体瘤微创手术136例分析  

An analysis of 136 cases underwent pituitary adenoma resection via single-nostril transsphenoidal approach

作　　者：蒋文庆[1] 顾培元[2] 胡卫星[2] 陈功[2] 顾斌[3] 魏栋[2] 

机构地区：[1]江苏大学附属武进医院神经外科,213017 [2]南京医科大学第一附属医院神经外科 [3]东南大学附属中大医院神经外科

出　　处：《江苏医药》2016年第19期2121-2122,2125,I0001,共4页Jiangsu Medical Journal

摘　　要：目的总结显微镜下单鼻腔经蝶垂体瘤微创手术的临床应用效果。方法回顾性分析136例显微镜下单鼻腔直接经蝶垂体瘤手术患者的临床资料。结果肿瘤全切124例,次全切除10例,大部分切除2例。术后内分泌功能恢复者61例,视力、视野恢复正常或有显著改善者29例。术后出现一过性尿崩者16例,难控制性尿崩者1例。术后3个月复查MRI发现肿瘤残余8例;其中,2例肿瘤呈侵袭性生长。无死亡及感染病例。结论显微镜下单鼻腔直接经蝶入路切除脑垂体瘤,具有手术创伤小、切除肿瘤相对完全、术后患者反应轻和恢复快的优点。Objective To summarize the clinical outcomes of pituitary adenoma resection by single-nostril transsphenoidal approach .Methods Clinical data of 136 cases with pituitary adenoma resected through single-nostril transsphenoidal approach were analyzed retrospectively .Results Among all cases ,124 cases accepted gross total resection ,10 cases nearly total resection and 2 cases subtotal resection .Endocrine functions recovered in 61 cases after surgery ,while vision and visual field were improved significantly in 29 cases .A total of 16 cases were complicated with postoperative transient diabetes insipidus ,and another one with intractable diabetes insipidus .MRI scanning taken in three months after surgery revealed that residual tumors occurred in 8 cases ,including 2 cases of invasive tumors .There was no infection or death .Conclusion Pituitary adenoma resection through single-nostril transsphenoidal approach has the advantages of minimal invasion ,complete removal of tumors ,less postoperative reaction and quick recovery .

关 键 词：垂体瘤 微创手术 

分 类 号：R736[医药卫生—肿瘤]