血清缺血修饰白蛋白检测在缺血性结肠炎诊断中的价值  

Value of detection of serum ischemia-modified albumin in diagnosis of ischemic colitis

作　　者：彭雪莲[1] 田继云[1] 曹勤[1] 

机构地区：[1]上海中医药大学附属普陀医院消化内科,上海市200062

出　　处：《世界华人消化杂志》2016年第28期4004-4007,共4页World Chinese Journal of Digestology

基　　金：上海中医药大学附属普陀医院院级资金资助项目;No.2013PT077~~

摘　　要：目的观察血清缺血修饰白蛋白(ischemia-modified albumin,IMA)对缺血性结肠炎(ischemic colitis,IC)患者早期诊断的价值,以寻找简便、经济、敏感的诊断方法 .方法收治2013-07/2016-04收治的IC患者60例(IC组),均经肠镜检查确诊.另收治同期住院时经肠镜检查正常者58例(对照组),均于入院后抽血检测血清IMA.应用SPSS22.0统计软件分析血清IMA对IC患者早期诊断的价值.结果经结肠镜检查确诊的60例IC患者,血清IMA平均水平为12.75 mg/L±3.51 mg/L;正常组患者58例,血清IMA平均水平为0.14 mg/L±0.02 mg/L,差异具有统计学意义(P<0.05).结论血清IMA在IC患者中,明显高于正常组患者水平,表明在IC患者早期,IMA可有效早期诊断IC的发生,简便、经济,值得临床推广.AIM To assess the diagnostic value of serum ischemia-modified albumin for ischemic colitis in order to find a simple,economical and sensitive diagnostic method for this disease.METHODS From July 2013 to April 2016,60 cases of ischemic colitis were diagnosed by colonoscopy.Fiftyeight patients who were hospitalized during the same period but had a normal colonoscopy were included as a control group.After admission,blood serum ischemia modified albumin levels were measured.Statistical analysis was then used to analyze the value of serum ischemia modified albumin in early diagnosis of ischemic colitis.RESULTS In 60 patients with ischemic colitis confirmed by colonoscopy,the average level of serum ischemia modified albumin was 12.75 mg/L±3.51 mg/L.In 58 patients in the control group,the average level of serum ischemia modified albumin was 0.14 mg/L ± 0.02 mg/L.There was a significant difference in serum ischemia modified albumin level between the two groups（P 0.05）.CONCLUSION Serum ischemia modified albumin is significantly higher in patients with ischemic colitis than in controls,suggesting that early detection of ischemia modified albumin can be helpful for the early diagnosis of ischemic colitis.

关 键 词：缺血修饰白蛋白 缺血性结肠炎 诊断 

分 类 号：R574.62[医药卫生—消化系统]