DWI及动态增强MRI定量检测在前列腺癌诊断中的应用  

The application value of the quantitative detection of diffusion weighted imaging and dynamic contrast-enhanced MRI in the diagnosis of prostate cancer

作　　者：王海宝[1] 刘灿[1] 贾媛[1] 马宁[1] 吴津明 WANG Hai-bao LIU Can JIA Yuan MA Ning WU Jin-ming(Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei Anhui 230022, Chin)

机构地区：[1]安徽医科大学第一附属医院放射科,安徽合肥230022

出　　处：《蚌埠医学院学报》2016年第9期1234-1236,共3页Journal of Bengbu Medical College

基　　金：国家自然科学基金项目(8171326)

摘　　要：目的:探讨弥散加权成像(DWI)和动态增强MRI(DCE-MRI)定量检测在前列腺良恶性病变鉴别诊断中的价值。方法:回顾性分析15例前列腺DWI和DKtransCE-MRI定量参数,包括表观扩散系数(ADC)、容积转运常数Ktrans、回流速率常数kep、血管外细胞外间隙体积比(ve)值。并运用SPSS进行统计学分析。结果:前列腺癌癌灶和增生灶的ADC、Ktrans和kep值分别为(1.21±0.26)mm2/s和(0.83±0.32)mm2/s、(0.45±0.22)min-1和(0.17±0.08)min-1、(0.95±0.44)min-1和(0.49±0.26)min-1,差异均有统计学意义(P<0.01)。结论:ADC、Ktrans、kep值在前列腺良恶性病变中存在显著不同,DWI和DCE-MRI定量评估对前列腺良恶性病变的鉴别具有一定的价值。Objective： To explore the value of quantitative detection of diffusion weighted imaging（DWI） and dynamic contrast- enhanced MRI（DCE-MRI） in the differentiation diagnosis of malignant and benign lesions of prostate. Methods： The quantitative parameters of DWI and DCE-MRI in 15 cases with prostate cancer were retrospectively analyzed. The quantitative parameters included the ADC, Ktrans, kep and vo, and which was statistically analyzed by SPSS. Results：The values of the ADC, Ktrens and kep in malignant lesion and benign lesion of prostate were （1.21 ±0.26） mm2/s and （0.83 ±0.32）mmZ/s,（0.45 ±0.22）min-1 and （0.17 ±0.08） min - l, and （0.95 ± 0.44 ） min - 1 and （ 0.49 ± 0.26 ） min - 1, respectively, the difference of which was statistically significant （ P 〈 0. 01 ）. Conclusions ： The values of the ADC, Ktrans and kcp between malignant lesion and benign lesion of prostate are different, and the quantitative assessment of DWI and DCE-MRI has certain value in the differentiation diagnosis of malignant lesion and benign lesion of prostate.

关 键 词：前列腺肿瘤 动态增强磁共振 弥散加权成像 定量评估 

分 类 号：R737.25[医药卫生—肿瘤]