Advances of Intracranial Electroencephalography in Localizing the Epileptogenic Zone  

作　　者：Bo Jin Norman K.So Shuang Wang 

机构地区：[1]Department of Neurology, Epilepsy Center, Second Affiliated Hospital, School of Medicine, Zhejiang University [2]Regional Epilepsy Center at Harborview, University of Washington

出　　处：《Neuroscience Bulletin》2016年第5期493-500,共8页神经科学通报（英文版）

基　　金：supported by the National Natural Science Foundation of China (81271435 and 91332202)

摘　　要：Intracranial electroencephalography（i EEG）provides the best precision in estimating the location and boundary of an epileptogenic zone. Analysis of i EEG in the routine EEG frequency range（0.5-70 Hz） remains the basis in clinical practice. Low-voltage fast activity is the most commonly reported ictal onset pattern in neocortical epilepsy, and low-frequency high-amplitude repetitive spiking is the most commonly reported ictal onset pattern in mesial temporal lobe epilepsy. Recent studies using wideband EEG recording have demonstrated that examining higher（80-1000 Hz） and lower（0.016-0.5 Hz） EEG frequencies can provide additional diagnostic information and help to improve the surgical outcome. In addition,novel computational techniques of i EEG signal analysis have provided new insights into the epileptic network.Here, we review some of these recent advances. Although these sophisticated and advanced techniques of i EEG analysis show promise in localizing the epileptogenic zone,their utility needs to be further validated in larger studies.Intracranial electroencephalography（i EEG）provides the best precision in estimating the location and boundary of an epileptogenic zone. Analysis of i EEG in the routine EEG frequency range（0.5-70 Hz） remains the basis in clinical practice. Low-voltage fast activity is the most commonly reported ictal onset pattern in neocortical epilepsy, and low-frequency high-amplitude repetitive spiking is the most commonly reported ictal onset pattern in mesial temporal lobe epilepsy. Recent studies using wideband EEG recording have demonstrated that examining higher（80-1000 Hz） and lower（0.016-0.5 Hz） EEG frequencies can provide additional diagnostic information and help to improve the surgical outcome. In addition,novel computational techniques of i EEG signal analysis have provided new insights into the epileptic network.Here, we review some of these recent advances. Although these sophisticated and advanced techniques of i EEG analysis show promise in localizing the epileptogenic zone,their utility needs to be further validated in larger studies.

关 键 词：Epilepsy Intracranial electroencephalography Epileptogenic zone 

分 类 号：R742.1[医药卫生—神经病学与精神病学]