450例非酒精性脂肪性肝病患者体质类型分布及伴随疾病的研究  

A clinical research of the TCM constitution type distribution and the complication of 450 NAFLD patients

作　　者：沈天白 李莹[1] 张玮[1] 李坤[2] 吕生霞 王晓飞[2] 

机构地区：[1]上海中医药大学附属龙华医院肝病科,上海200032 [2]上海中医药大学

出　　处：《中西医结合肝病杂志》2016年第5期260-262,306,共4页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

基　　金：国家自然科学基金项目(No.81403357);上海市卫生局科研项目(No.20124041)

摘　　要：目的:观察非酒精性脂肪性肝病(NAFLD)患者体质类型分布与伴随疾病之间的相关性,为中医药对NAFLD患者的辨证施治及疾病预后评估提供临床证据。方法:共收集450例NAFLD患者进行中医体质分析,同时观察其体质类型与2型糖尿病、高血压病、冠心病、高尿酸血症、甲状腺疾病及脑血管疾病患病率的相关性。结果:450例NAFLD患者的主要体质类型分别是痰湿质为172(38.2%)、阴虚质112(24.9%)、气虚质112例(24.9%)。不同体质类型NAFLD患者的伴随疾病患病率各不相同,其中痰湿质患者的2型糖尿病患病率高于其他体质类型(尸<0.05);血瘀质患者冠心病的患病率高于其他体质类型(P<0.05)。结论:NAFLD患者的体质类型多为偏颇体质,其中以痰湿质、气虚质、阴虚质为主,且痰湿质患者的2型糖尿病患病率、血瘀质患者的冠心病患病率高于其他体质类型。Objective： To observe the TCM constitution type distribution of patients with NAFLD and the correlation between the complica- tion to provide a clinical basis for evaluate prediction and treat NAFLD in traditional Chinese medicine. Methods：Four hundred and fifty NAFLD cases were categorized by traditional physical in this study and the correlation between the TCM constitution type and the morbidity rate of type 2 diabetes, hypertensive, coronary heart disease, hyperuricemia, thyroid diseases and cerebrovaseular diseases were compared, respectively. Results： Four hundred and fifty cases of patients with NAFLD TCM constitution mainly phlegm-wetness type （ including simple phlegm-wetness type and combine other type, the same below） is 172 cases（38.2% ）, qi-deficiency type is 112 cases （24.9%） and yin-de- ficiency type is 112 cases （24.9%）. Each TCM constitution type has different morbidity rate. The NAFLD patients with phlegm-wetness type had the highest morbidity rate of type 2 diabetes among different physical type of NAFLD patients （P 〈 0.05） and blood stasis type had the highest morbidity rate of coronary heart disease （ P 〈 0.05 ）. Conclusion： The mainly TCM constitution of NAFLD patients were phlegm-wet- hess type, qi-deficiency type and yin-deficiency type. NAFLD patients with phlegm-wetness type had higher prevalence rate of type 2 diabet- estype 2 diabetes than the others. And blood stasis type had the highest prevalence rate of coronary disease.

关 键 词：中医体质 非酒精性脂肪性肝病 

分 类 号：R575[医药卫生—消化系统]