丹参多酚酸盐注射液治疗急性脑梗死的效果分析  

Effect analysis of Salvia miltiorrhiza injection in the treatment of acute cerebral infarction

作　　者：朱秋艳 

机构地区：[1]江西省宜春市人民医院神经内科,江西宜春336000

出　　处：《中国当代医药》2016年第29期138-140,共3页China Modern Medicine

摘　　要：目的 分析丹参多酚酸盐注射液治疗急性脑梗死的临床效果。方法 选择我院2013年1月~2014年6月收治的抗血小板、强化降脂、改善脑循环等常规方法治疗的脑梗死患者50例,作为对照组;另选取同时间段收治的在常规方法治疗基础上联合丹参多酚盐酸注射液治疗的脑梗死患者50例,作为观察组。比较两组患者治疗后的治疗效果、不良反应情况以及两组患者治疗前后的卒中量表（NIHSS）评分、C反应蛋白（CRP）、肿瘤坏死因子-α（TNF-α）、红细胞聚集指数。结果 观察组患者的治疗有效率（96.0%）高于对照组（76.0%）,不良反应发生率（4.0%）低于对照组（24.0%）,差异有统计学意义（P〈0.05）。治疗前两组的NIHSS评分、CRP、TNF-α、红细胞聚集指数比较,差异无统计学意义（P〉0.05）;治疗后两组患者的NIHSS评分、CRP、TNF-α、红细胞聚集指数等均优于治疗前,且观察组的改善效果优于对照组（P〈0.01）。结论 丹参多酚酸盐注射液治疗急性脑梗死效果显著,可有效改善患者的血流动力学,降低炎性反应,且不良反应低,可在临床进行推广。Objective To analyze the clinical effect of Salvia miltiorrhiza injection in the treatment of acute cerebral infarction.Methods 50 cases of cerebral infarction treated in our hospital from January 2013 to June 2014 were treated with anti platelet,intensive lipid lowering,improvement of cerebral circulation and other conventional methods were se- lected as the control group;50 patients with cerebral infarction were selected from the same period combined with Salvia miltiorrhiza injection in the treatment of hydrochloric acid polyphenols in the conventional methods based on the treatment of the patients in the control group.The therapeutic effect,adverse reactions and the two groups before and af- ter treatment in patients with the NIHSS score,C-reactive protein （CRP）,tumor necrosis factor-ct（TNF-α）,rcd blood cell aggregation index of two groups were compared.Results The treatment efficiency of the observation group （96.0%） was higher than that of the control group （76.0%）,the incidence of adverse reaction （4.0%） was lower than that of the control group （24.0%）,the difference was statistically significant （P〈0.05）.Before treatment,the NIHSS score,CRP,TNF-α,ery- throcyte aggregation index of the two groups had no statistical difference （P〉0.05）;after treatment, the NIHSS score, CRP,TNF-α,red blood cell aggregation index of two groups were better than that of before treatment and observation group was better than control group （P〈0.01）.Conclusion Salvia mihiorrhiza injection in the treatment of acute cerebral infarction has a significant effect,can effectively improve the patients＇ hemodynamics,reduce the inflammatory reaction, and adverse reaction is low,can be popularized in clinic.

关 键 词：丹参多酚酸盐注射液 急性脑梗死 红细胞聚集指数 

分 类 号：R743.3[医药卫生—神经病学与精神病学]