计算机断层扫描模拟定位扫描层厚对不同大小靶区勾画的影响  

Effect of scanning layer thickness on different sized target delineation in computed tomography simulated location

作　　者：夏士安[1] 王佳[1] 王为[1] 

机构地区：[1]上海交通大学医学院附属新华医院肿瘤放疗科,上海200092

出　　处：《中国肿瘤临床与康复》2016年第10期1166-1168,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨计算机断层扫描(CT)扫描层厚对不同大小靶区勾画和肿瘤靶区体积(GTV)的影响。方法在Phlips CT模拟定位机上,应用层厚分别为2 mm、3 mm、5 mm的条件,分别对4个不同体积的人体等效组织的蜡块进行扫描,然后在Eclips(放疗模拟工作站)上逐层画出物体的外轮廓,利用工作站的统计功能计算出4个被测物体的体积。结果被测物体体积和物体体积大小误差与扫描层厚呈正比例关系。结论临床医生在确定临床靶区体积时,需要考虑到靶区体积与扫描层厚的厚度范围密切相关,差异变化程度与靶区体积大小呈负相关,靶区越小,差异变化程度越大,随着扫描层厚的变薄,扫描得到的靶区体积越接近实际的肿瘤体积。Objective To explore the effect of scanning layer thickness in computed tomography（ CT） on different sized target delineation and tumor target volume（ GTV）. Methods Using Phlips CT simulator,with layer thickness of 2 mm,3 mm and 5 mm,wax blocks of 4 different volumes of human equivalent tissues were scanned respectively,and then the outline of each object was drawn layer by layer in Eclips（ radiotherapy simulation workstation）. The volume of the 4 objects was calculated by the statistical function of the workstation. Results The volume of the objects measured and error of the measurements were positively associated with the range of scanning layer thickness. Conclusions When determining the clinical target volume,clinicians need to take into account that the size of the target area was closely associated with the thickness of the scanning layer. The degree of variation is negatively associated with the volume of the target area. The smaller the target area,the greater the degree of variation. The volume of the target region is close to the actual tumor volume as the scanning layer thickness becomes thinner.

关 键 词：计算机断层扫描 层厚 靶区勾画 

分 类 号：R730.44[医药卫生—肿瘤] R730.55[医药卫生—临床医学]