64排螺旋CT对原发性胆汁性肝硬化患者肝脏体积变化的研究——与乙肝肝硬化和正常人对比研究  

Investigation of Liver Volume Change of Primary Biliary Cirrhosis Compared to Hepatitis B Virus-Related Cirrhosis by 64-Slice Spiral CT

作　　者：符玉环[1] 贺文[1] 王克扬[1] 

机构地区：[1]首都医科大学附属北京友谊医院放射科,100050

出　　处：《临床放射学杂志》2016年第10期1517-1520,共4页Journal of Clinical Radiology

摘　　要：目的应用64排螺旋CT测量肝脏体积,探讨原发性胆汁性肝硬化(PBC)失代偿期患者肝脏体积变化的特点。方法搜集PBC住院患者48例作为PBC组,同期搜集乙型肝炎病毒相关肝硬化患者64例作为HBC组,并随机选取同期52例正常人作为对照组,所有病例均行腹部CT增强扫描,将门静脉期图像分解后所获得的轴面图像数据传输至GE Advantage Workstation 4.4,重建并计算出肝脏体积,计算出标准化的肝脏体积后,应用SPSS15.0统计软件,对三组肝体积均数的总体差异和两两组间差异进行比较。结果 (1)比较PBC组、HBC组、对照组的CT测量肝脏体积和标准化肝体积的差异均有统计学意义(F=7.435,P=0.024;F=4.862,P=0.012);(2)分别比较两两组间CT测量肝脏体积和标准化肝体积的差异,其中PBC组与HBC组之间、HBC组与对照组之间的差异均有统计学意义(P<0.05),PBC组与对照组的差异均无统计学意义(P>0.050)。结论 PBC倾向好发于女性,失代偿期肝脏体积缩小不显著,部分仍呈弥漫性增大。Objective To explore the value of 64-slice spiral CT on the change of liver volume in patients with primary biliary cirrhosis. Methods Collecting 48 patients with PBC,64 patients with hepatitis B virus-related cirrhosis and 52 patients with no liver disease as control group. Enhanced CT Abdomen was performed in each patient and the axial images of portal venous phase were transferred to GE Advantage Workstation 4. 4. The standardized liver volumes of each group were analyzed with SPSS 15. 0. Results（ 1） The differences of the liver volume and the standardized liver volume by CT have statistical significance in these groups（ F = 7. 435、P = 0. 024,F = 4. 862、P = 0. 012）;（ 2） Compare the liver volume and the standardized liver volume between every two groups,differences were observed between the PBC group and HBC group. The HBC group and control group have statistical significance（ P〈0. 05） and there is no statistical significance between PBC group and the control group（ P〉 0. 050）. Conclusion PBC tends to occur in females. In the decompensated period,the liver volume shrinking is not significant and part of them having diffuse enlargement.

关 键 词：64排螺旋CT 原发性胆汁性肝硬化 肝脏体积 

分 类 号：R575.2[医药卫生—消化系统]