溶血磷脂酸受体6  

Lysophosphatidic acid receptor 6

作　　者：李铁威[1,2] 赵鹏飞[1] 贠庆茹 阿拉坦高勒[1] 

机构地区：[1]内蒙古大学生命科学学院,呼和浩特010021 [2]北京协和医学院,中国医学科学院,阜外心血管病医院,国家心血管病中心,北京100000

出　　处：《生命的化学》2016年第5期650-654,共5页Chemistry of Life

基　　金：国家自然科学基金项目(31260210)

摘　　要：溶血磷脂酸受体6(lysophosphatidic acid receptor 6,LPA6)作为最晚确定的溶血磷脂酸(lysophosphatidic acid,LPA)受体,近年来多项研究发现LPA6参与毛囊发育过程,与人体毛发稀少症存在相关性;并可减弱细胞间的粘附作用。且最近相关研究报道指出,LPA6在肿瘤的发展过程中同样扮演重要角色。本文将汇集LPA6相关知识,对其研究现状进行综述。Lysophosphatidic acid receptor 6（LPA6）, as the latest identified lysophosphatidic acid receptor, has been demonstrated by several studies that it participates in the development of hair follicle and is associated with the disease of hypotrichosis in recent years. In addition, LPA6 can also reduce the cell adhesion. Moreover, LPA6 also been reported that it play an important role in the development of tumor process recently. This article will focus on the related knowledge of LPA6 to introduce the research progress of LPA6.

关 键 词：溶血磷脂酸受体6 毛发稀少症 肿瘤 

分 类 号：R363[医药卫生—病理学]